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Preterm growth failure after birth

Incidence of postnatal growth restriction in preterm infants at Dubai hospital

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12618000434291
Enrollment
55
Registered
2018-03-26
Start date
2018-04-05
Completion date
2019-09-26
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Postnatal growth restriction (PNGR) is a common problem facing neonatologists in the era of improved survival of extreme preterm infants. Considerable number of preterm infants fail to achieve the intrauterine growth accretion parameters after birth inspite of aggressive nutritional strategies carried by NICU staff. PNGR is a potential risk factor for the future neurodevelopmental outcome of preterm infants. The objective of the current prospective observational study is to evaluate the incidence of PNGR at NICU, Dubai Hospital with assessment of all growth parameters namely weight, head circumference, and length. Evaluation will be on weekly basis starting since birth till the age of 40 weeks corrected gestational age or the time of discharge. The secondary outcome is to evaluate the nutritional strategy adopted by NICU to achieve the desired caloric intake either by parentral nutrition or enteral intake.

Interventions

The nutritional management of preterm infants represents a crucial challenge for most of practitioners caring of sick premature babies. And despite the aggressive parenteral and enteral alimentation, yet a considerable number still fall far beyond the expected growth indices that match infants of similar gestation in-utero. The incidence of post-natal growth restriction (PNGR) varied and ranged from 37% to 67% in preterm infants. PNGR can have detrimental neurodevelopmental outcome and cogniti

The nutritional management of preterm infants represents a crucial challenge for most of practitioners caring of sick premature babies. And despite the aggressive parenteral and enteral alimentation, yet a considerable number still fall far beyond the expected growth indices that match infants of similar gestation in-utero. The incidence of post-natal growth restriction (PNGR) varied and ranged from 37% to 67% in preterm infants. PNGR can have detrimental neurodevelopmental outcome and cognitive impairment during later stages of life. The purpose of this observational study is to evaluate the nutritional strategy and explore the incidence of PNGR among preterm infants admitted to NICU, Dubai Hospital. Preterm infants<32 weeks and birth weight <1500gm will be subjected to serial measurments of growth indices mainly weight, length and head circumference on weekly basis after birth till time of discharge or when reaching 40 weeks corrected age. The caloric intake either enteral or parentral via TPN will be calculated and recorded including all the constiuents of parentral nutrition.

Sponsors

Dubai hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
1 Hours to 16 Weeks
Healthy volunteers
No

Inclusion criteria

All preterm infants with gestational age ranging from 24- 32 weeks and birth weight of 500 gram- 1499 gram admitted to NICU Dubai hospital during the study period.

Exclusion criteria

1- infants with major congenital abnormalities. 2-infants with antenatal diagnosis of small for gestational age (SGA). 3-infants more than 32 weeks gestation, or birth weight more than 1500 gram.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026