None listed
Conditions
Brief summary
An amendment to the ethics committee to include people with heart failure was submitted on 28/11/2018 and approved on 17/12/2018. The aim of the study is to determine if one session of exercise on a treadmill or cycle ergometer will alter the cognitive function in people with COPD or heart failure Patients wit COPD or heart failure will be recruited from pulmonary rehabilitation and randomised via computerised randomisation generation to either the treadmill/cycle group or the quiet sitting group. Participants complete the MoCa Version 7.1 and COPD participants will be asked to walk on the treadmill for 20 minutes at 80% of the average six-minute walk test speed calculated from the better of two six-minute walk tests. Participants with heart failure will be asked to cycle on a stationary cycle ergometer for 20 minutes at 60% of their peak exercise capacity calculated from the better of two six-minute walk tests. At completion of the exercise, participants will rest until oxygen saturation, heart rate and breathlessness returns to pre exercise levels. At this point participants will be asked to complete the MoCa Version 7.2, For the quiet sitting, participants will complete the MoCa version 7.1 and then be asked to sit in a quiet room and listen to music of their choice for 20 minutes, following which they will complete MoCa version 7.2. Two version of the MoCa will be used to control for test familiarity of repeated testing.
Interventions
Participants with COPD will be invited to participate in this study
If they agree they will be consented and randomised into either the intervention group (IG) or the control group (CG)
The IG will complete the Montreal Cognitive Assessment (MoCa) (measure of cognitive impairment), then perform 20 minutes walking on a treadmill (walk speed determined from 80% of the six-minute walk test). They will then complete the MoCa again. The MocCa is administered by the physiotherapist in a quiet room in
Participants with COPD will be invited to participate in this study If they agree they will be consented and randomised into either the intervention group (IG) or the control group (CG) The IG will complete the Montreal Cognitive Assessment (MoCa) (measure of cognitive impairment), then perform 20 minutes walking on a treadmill (walk speed determined from 80% of the six-minute walk test). They will then complete the MoCa again. The MocCa is administered by the physiotherapist in a quiet room in the outpatients department and takes about 30 minutes maximum to deliver. The delivery is face to face and one on one. The 6MWT is performed as part of initial assessment for pulmonary rehabilitation before recruitment occurs. The MoCA has been used as a screening instrument for moderate cognitive impairment by assessing memory, language, executive functions, visuospatial skills, calculation, abstraction, attention, concentration and orientation. There are alternate forms of the MoCA and version 2 will be used at T2
Sponsors
Royal Prince Alfred Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Diagnosis of COPD or heart failure
Exclusion criteria
Neurological or musculo skeletal problems - so unable to perform treadmill walking or stationary cycling. Diagnosis of dementia Inability to read and/or understand the MoCa questionnaire
Outcome results
None listed