Impact of progestin induced period on the outcome of clomid ovulation induction in women with polycystic ovary syndrome.

Impact of progestin induced withdrawal bleeding on the outcome of ovulation induction with clomiphene citrate in women with polycystic ovary syndrome.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12618000259246

Enrollment

100

Registered

2018-02-16

Start date

2014-05-24

Completion date

2017-05-20

Last updated

2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Women with polycystic ovary syndrome (PCOS) are anovulatory and oligomenorrheic. Clomiphene citrates is the first line drug used to induce ovulation and achieve pregnancy in these women. The study aims to find if induced withdrawal bleeding using progestin has an impact on success of ovulation, endometrium, and pregnancy in these women.

Interventions

ovulation induction using clomiphene citrates oral tablets in the dose of 100 mg daily for 5 days following induced menstrual period by dydrogesterone oral tablets in the dose of 30 mg for 7 days. Compliance with the intervention was assured by return of empty tablet strips.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Healthy volunteers

Inclusion criteria

Women with polycystic ovary syndrome

Exclusion criteria

Other causes of infertility

Outcome results