None listed
Conditions
Brief summary
Purpose of Research To introduce the use and investigate the safety and efficacy of Mohs Micrographic Surgery(MMS) in the treatment of periocular basal cell carcinoma (BCC) in Hong Kong. Expected Duration Participants are seen by the ophthalmologist and we will try to arrange the removal of the mass within next 2 weeks. Participants will be seen at postoperative week 1, 4, 12, 26 and 52 to look for any surgical complication and recurrence. Main Outcome and Measures Clinical and histological characteristics of tumors, layers of MMS procedures, complications and biopsy-confirmed recurrence at the same location. Potential Risks or Discomfort There may be some discomfort during the procedure. Excision of tumor will leave a scar and may damage certain important structure around the eye. Participants' eyelid may droop or may not close well. There is always a risk of recurrence or metastasis of the tumor. Potential Benefits MMS offers the best chance of cure and lowest recurrence rate as the treatment of skin cancer in other parts of the body. Overseas evidences also favor the use of MMS in the treatment of periocular BCC.
Interventions
Patients received Mohs Micrographic Surgery(MMS) under a streamlined standard operating procedure emphasizing surgeon-driven mapping, specimen-orientation and clinico-histological correlation with the dermatopathologist at the frozen-section laboratory.
The tumor will be removed in the operating theatre after you have received adequate local anesthesia. It will be carefully marked and sent to the pathology laboratory. The pathologist is going to make very thin cut of the mass and examine the
Patients received Mohs Micrographic Surgery(MMS) under a streamlined standard operating procedure emphasizing surgeon-driven mapping, specimen-orientation and clinico-histological correlation with the dermatopathologist at the frozen-section laboratory. The tumor will be removed in the operating theatre after you have received adequate local anesthesia. It will be carefully marked and sent to the pathology laboratory. The pathologist is going to make very thin cut of the mass and examine the margin carefully. Any remaining tumor will be excised and this procedure will be repeated until all tumor parts are removed. The wound will then be closed on the same day or the next.
Sponsors
The Chinese University of Hong Kong
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Biopsy proven or clinically suspicious BCC 2. Lesion located from zone I to IV with or without extension to zone V of the eye skin 3. Informed consent
Exclusion criteria
1. Non-BCC skin cancer 2. Previously treated (residual, recurrent) BCC 3. Refusal for surgery or follow-up
Outcome results
None listed