None listed
Conditions
Brief summary
The aim of this RCT is to determine if there are any benefits of placing dental implants into sites that have previously received alveolar ridge preservation (ARP) when compared to conventional implant placement protocol. This study will be carried out on patients recruited from a specialist clinical practice who are referred for single implant replacement in the aesthetic zone (teeth 13-to-23) and who meet the inclusion criteria.
Interventions
Alveolar ridge preservation (ARP): upon extraction, an alveolar ridge preservation procedure is performed using anorganic bovine bone mineral stabilized in 10% porcine type-1 collagen matrix (ABBM-C) (Bio-Oss Collagen®) and covered with a type 1 and 3 non-cross linked porcine collagen matrix seal (CMS) (Mucograft Seal®). Implant placement will take place 12 weeks later. All surgical interventions will be administered by a specialist periodontist.
Sponsors
University of Queensland
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• Over 18 years of age, medically healthy or mild controlled systemic disease • Required the replacement of single tooth in the anterior maxilla with an implant supported restoration and was bounded by natural teeth. • The tooth is in-vivo • No evidence of acute infection • Implant primary stability can be achieved using an early implant placement protocol • Adequate plaque control (full mouth plaque and bleeding on probing (BOP) scores less than or equal to 25%). • Treated periodontal disease deemed to be stable and patients are enrolled into a supportive periodontal program.
Exclusion criteria
• Advanced buccal wall defects • Required multiple implant replacement either adjacent or part of a multi-unit implant supported restoration • Less than 2mm of gingival tissue height on the buccal aspect • A systemic medical condition that could interfere with surgical procedure or negatively impact bone turnover • Pregnancy at the time of recruitment • A physical handicap that would interfere with the ability to perform adequate oral hygiene • Self-reported smoking of more than 10 cigarettes per day • A reported history of local radiation therapy • Untreated / unstable periodontal disease
Outcome results
None listed