Optical coherence tomography angiography in healthy subjects and patients with retinal vascular diseases.

Evaluation of optical coherence tomography angiography parameters in healthy subjects and patients with retinal vascular diseases.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12617001633370

Enrollment

150

Registered

2017-12-15

Start date

2015-01-16

Completion date

2018-06-01

Last updated

2018-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Optical coherence tomography angiography is a new imaging technique for retinal and choroidal vasculature.Diabetic retinopathy and retinal vein occlusion are the most common retinal vascular diseases which lead to significant vision loss due to retinal ischemia and macular edema. Coats disease is an idiopathic retinal vascular disease characterised by telangiectasia and exudative retinopathy. In this study we do retrospective and prospective analysis of OCTA images of patients with retinal vascular diseases and a group of healthy volunteer who have undergone OCTA at Lions eye institute from 2015 to 2018 .These patients are identified through database search of all patients . Patients who have given consent for their retinal images to be used for research are eligible. The aim of the study to measure the vascular density and foveal avascular zone in patients with retinal vascular diseases and healthy volunteers. In addition, to compare the vascular density between the diseased subjects and healthy controls.

Interventions

Optical coherence tomography angiography (OCTA) is a novel imaging technique that enables three dimensional images of retinal and choroidal vasculature.In this study OCTA is performed using the RTVue XR Avanti device (ReVue software, Optovue Inc, Fremont, California, USA) with the Angio Retina mode (3×3 mm ) by experienced technicians. Each OCTA volume is acquired in approximately 3 seconds and 2 orthogonal OCTA volume are acquired to perform motion correction. Retinal images are evaluated and g

Eligibility

Sex/Gender

All

Age

10 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Patients with retinal vascular diseases, including diabetic retinopathy, retinal vein occlusion and Coats’ disease, are considered for this study. Both, treatment naïve and previously treated patients are included.and healthy volunteer which are age matched and have no retinal diseases

Exclusion criteria

Patients with poor image quality with low signal score Patients with retinal disease other than diabetic retinopathy, retinal vein occlusion and Coats’ disease healthy volunteer who are not age matched

Outcome results