None listed
Conditions
Brief summary
Myopia of any degree increases the risk of developing sight-threatening conditions such as glaucoma, retinal detachment and myopic maculopathy with risk increasing dramatically with progression to high myopia. Atropine eye drops are currently the most effective treatment for managing myopia progression, but the mode of action is unclear. The aim of this study was to investigate the effect of atropine eye drops on choroidal thinning induced by hyperopic retinal defocus, using automated measures of choroidal thickness obtained with swept-source optical coherence tomography (SS-OCT). A secondary aim was to record the short-term effect of atropine on the resting thickness of the choroid.
Interventions
One drop 0.5% atropine eye drop to non-dominant eye on one occasion, instilled by the research optometrist
Sponsors
The University of Auckland
Study design
Allocation
Non-randomised trial
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
The inclusion criteria for this study were: Spherical Equivalent Refraction (SER) with spectacle prescription between -1.00 to -5.00 D, with little astigmatism (= 1.00 D) or anisometropia (= 1.00 D).
Exclusion criteria
Individuals with amblyopia, ocular pathology or other ocular anomalies (e.g. surgery, trauma) that might have influenced the measurements were excluded.
Outcome results
None listed