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Assessment of a quality improvement program for the management of patients undergoing bowel resection

Assessment of a quality improvement program´s effect on the anastomotic leakage rate for patients undergoing colorectal resections.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12617001497392
Enrollment
894
Registered
2017-10-24
Start date
2014-02-14
Completion date
2015-04-24
Last updated
2017-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Failure of healing bowel joints after surgery constitutes a serious clinical problem. The purpose of this study is to assess if a quality improvement program at the Karolinska University Hospital can reduce the risk for complications after bowel surgery. The hypothesis is that structured changes in clinical practice can reduce the risk of leakage in surgically constructed bowel joints. The different components that constitutes the program have been suggested to improve surgical outcomes in previous studies. The outcomes for patients operated before and after the implementation of the quality improvement program will be compared.

Interventions

A quality improvement program for all patients undergoing colorectal resections at the Karolinska University Hospital (Section of coloproctology). The program contains three key elements and was implemented in January 2010. The post implementation study period was January 2010-December 2013. 1. Exclusion of nonsteroidal anti-inflammatory drugs peri-operatively from 5 days before surgery to 7 days after surgery.. 2. Introduction of intra-operative goal-directed fluid therapy. This was managed by

A quality improvement program for all patients undergoing colorectal resections at the Karolinska University Hospital (Section of coloproctology). The program contains three key elements and was implemented in January 2010. The post implementation study period was January 2010-December 2013. 1. Exclusion of nonsteroidal anti-inflammatory drugs peri-operatively from 5 days before surgery to 7 days after surgery.. 2. Introduction of intra-operative goal-directed fluid therapy. This was managed by stroke volume optimization using esphageal Doppler (CardioQ-ODM, Deltex Medical, Chichester, UK). 3. Avoidance of primary anastomoses in emergency resections. Surgeons were instructed to avoid emergency oncological resections of obstructing cancers by instead performing temporary defunctioning ostomies or avoid primary anastomosis if emergency resection was unavoidable (i.e. bowel perforation or severe bleeding).

Sponsors

Henrik Iversen
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Consecutive patients operated with colorectal resections with primary anastomosis at the Section of coloproctology at the Karolinska University Hospital during four years up to the implementation of a quality improvement program, and during four years after the implementation.

Exclusion criteria

No patients are excluded if they meet the inclusion criteria

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 25, 2026