None listed
Conditions
Brief summary
Hypothesis: Diagnostic lung ultrasound may be a useful non-invasive bedside tool to assist with clinical decision making during veno-venous-extracorporeal membrane oxygen support and requires further investigation. Objectives Primary: Can diagnostic lung ultrasound be used to monitor the movement of air in the lungs of patients who require on veno-venous ECMO? Secondary: To study the changes of in the movement of air in the lungs using lung ultrasound in comparison to standard measures of lung function and chest X-ray changes up to the point of weaning a patient from extra-corporeal membrane oxygenation Study design Prospective observational cohort study of 10 patients LUS assessment will be undertaken within 48-hours after commencement of ECMO and at 5 and 10 days after ECMO commencement. Standard measurements for VV-ECMO, including ECMO settings (sweep flow, ECMO flow) and arterial blood gases will be undertaken 4-6 hourly and recorded. The portable anterior chest radiograph will undertaken once per day and as clinically indicated.
Interventions
Diagnostic lung ultrasound (LUS) will be conducted within 48-hours of commencement of extracorporeal membrane oxygenation (ECMO), then again on day 5 and day 10 after the commencement of ECMO (or on the day of ECMO de-cannulation). The diagnostic lung ultrasound will be performed by a trained physiotherapist. The patient will be imaged in supine with the head of bed elevated 30-45 degrees dependent on device/patient stability. The intensive care unit has a dedicated portable ultrasound unit (S
Diagnostic lung ultrasound (LUS) will be conducted within 48-hours of commencement of extracorporeal membrane oxygenation (ECMO), then again on day 5 and day 10 after the commencement of ECMO (or on the day of ECMO de-cannulation). The diagnostic lung ultrasound will be performed by a trained physiotherapist. The patient will be imaged in supine with the head of bed elevated 30-45 degrees dependent on device/patient stability. The intensive care unit has a dedicated portable ultrasound unit (Sonosite Edge) and for this study the convex array probe (3 to 5 MHz) will be used.
Sponsors
George Ntoumenopoulos
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Blinded (masking used) (Caregiver)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age>18 years 2. Require veno-venous ECMO 3. Patient/next of kin willingness to give written informed consent and willingness to participate in and comply with the study.
Exclusion criteria
1. Unable to maintain patient position required for optimum ultrasound imaging 2. Body habitus prevents optimum ultrasound imaging
Outcome results
None listed