None listed
Conditions
Brief summary
The Cardiovascular Risk in Young Finns Study (YFS) is one of the largest follow-up studies into cardiovascular risk from childhood to adulthood. The main aim of YFS is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases in adulthood. In the current study, we used data from YFS to describle the association of childhood, as well as the average from childhood to adulthood, serum 25-hydroxyvitamin D levels with the risk of impaired fasting glucose and type 2 diabetes mellitus.
Interventions
Childhood serum 25-hydroxyvitamin D (25OHD) levels were measured in 2010 using serum samples taken in 1980 and stored at -20°C. Serum 25OHD levels were remeasured using serum samples taken in 2001 (1094 measured by 2003 and the rest during 2011) and 2007 (measured in 2008). The Cardiovascular Risk in Young Finns Study is a multi-centre population-based follow-up study of cardiovascular risk factors in Finland(Raitakari OT, Juonala M, Rönnemaa T, Keltikangas-Jarvinen L, Rasanen L, Pietikainen M,
Childhood serum 25-hydroxyvitamin D (25OHD) levels were measured in 2010 using serum samples taken in 1980 and stored at -20°C. Serum 25OHD levels were remeasured using serum samples taken in 2001 (1094 measured by 2003 and the rest during 2011) and 2007 (measured in 2008). The Cardiovascular Risk in Young Finns Study is a multi-centre population-based follow-up study of cardiovascular risk factors in Finland(Raitakari OT, Juonala M, Rönnemaa T, Keltikangas-Jarvinen L, Rasanen L, Pietikainen M, Hutri-Kahonen N, Taittonen L, Jokinen E, Marniemi J, et al. Cohort profile: the cardiovascular risk in Young Finns Study. Int J Epidemiol 2008;37(6):1220-6.). In 1980 (baseline), 3,596 participants aged 3-18 years were randomly selected from the national register of the study areas. They were followed up in 2001, 2007 and 2011, when 2283, 2204 and 2060 (aged 34-50 years) participants were re-examined, respectively.
Sponsors
University of Tasmania
Eligibility
Sex/Gender
All
Age
3 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
children and adolescents aged 3, 6, 9, 12, 15 and 18 years in all five Finnish university cities with medical schools and their rural surroundings.
Exclusion criteria
1. Participants who had Type 1 diabetes (n = 20) or were pregnant at each follow-up visits (n=91) were excluded from all analyses. 2. Participants who did not have complete risk factor data from baseline or adult T2DM data available from the 2001, 2007 or 2011 surveys.
Outcome results
None listed