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Comparison of nerve blocks applied for preventing muscle contractions in bladder tumor surgeries

Comparison of classic and inguinal obturator nerve blocks applied for preventing adductor muscle contractions in bladder tumor surgeries: A prospective randomized trial

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12617001050347
Enrollment
61
Registered
2017-07-18
Start date
2017-07-30
Completion date
2017-10-01
Last updated
2018-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Aim: Obturator nerve block (ONB) has been performed in surgeries of transurethral resection of bladder tumors (TUR-BT) for the prevention of the development of obturator muscle contraction. Currently, classic and inguinal approaches are frequently being used. In the present study, we aimed to compare the success rate, performance speed, and complication risks of both approaches. Method: Sixty-six patients who underwent TUR-BT under spinal anesthesia are randomly selected, and ONB is performed on the tumor location side using classic (n=33) or inguinal (n=33) approaches. Ten milliliters of 0.25% bupivacaine are administered using a peripheral nerve stimulator in both approaches. The duration of the determination of the obturator nerve, number of interventions, development of contractions, and complications are recorded.

Interventions

Before surgery, 500 mL intravenous 0.9% NaCl is administered to the patients. Heart rate, SpO2, blood pressure, and electrocardiography are monitored in the operating room. Spinal anesthesia is performed using 12.5 mg hyperbaric bupivacaine after insertion of a 25-gauge Quincke spinal needle from L3-4 or L4-5 in the sitting position. Patients are laid in the supine position. Development of sensory block is examined at the T10 level. Required anatomic markings were made on the wall where the t

Before surgery, 500 mL intravenous 0.9% NaCl is administered to the patients. Heart rate, SpO2, blood pressure, and electrocardiography are monitored in the operating room. Spinal anesthesia is performed using 12.5 mg hyperbaric bupivacaine after insertion of a 25-gauge Quincke spinal needle from L3-4 or L4-5 in the sitting position. Patients are laid in the supine position. Development of sensory block is examined at the T10 level. Required anatomic markings were made on the wall where the tumor was located by the approach to be applied: In the classic method, the puncture point is marked 1.5 cm lateral of tuberculum pubis and 1.5 cm caudal. In the inguinal method, the tuberculum pubis, spina iliaca anterior superior, inguinal ligament, and femoral artery are marked. The puncture entry point is determined as the middle of the tuberculum pubis and femoral artery, and 5-8 cm below the inguinal ligament. Obturator nerve block (ONB) has been performed in surgeries of transurethral resection of bladder tumors (TUR-BT) for the prevention of the development of obturator muscle contraction. Currently, classic and inguinal approaches are frequently being used. Patients are randomized for classic (n=33) and inguinal (n=33) ONBs. Simple randomization is done before study commencement by the Excel (Microsoft, Redmond, WA, USA) random number generation function. Adductor muscle contractions that occurred during the resection are recorded by a urologist who is blinded to the ONB technique. The peripheral nerve stimulator (Pajunk, Melsungen, Germany) is adjusted to 1.5 mA 1 Hz. Insertion is applied from the determined points using an isolated 22-gauge, 100-mm nerve stimulator needle (Pajunk, Melsungen, Germany). The needle is directed cephalad in the inguinal approach. In the classic method, the needle is perpendicularly inserted and slightly withdrawn after reaching the bone; the needle is manipulated 2-4 cm towards the medial. First, suction is performed, and then ten mL 0.25% bupivacaine are administered when an adductor muscle contraction area is detected with the peripheral nerve stimulator between the range of 0.4-0.7 mA. All ONB and TUR-BT procedures are performed by the same anesthesiologists and urologists.

Sponsors

Recai Dagli
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Caregiver)

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

Patients who have lateral wall bladder tumor and will be performed the Transurethral resection of bladder tumors (TUR-BT) under spinal anesthesia. Patients who are American Society of Anesthesiologists (ASA) risk grade I-III and aged between 18-80 years are included in the study.

Exclusion criteria

Patients who had undergone previous surgery in the study region and had anatomic disorders, neurologic problems, muscle disease, and coagulation disorders are excluded.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 4, 2026