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The effect of anesthesia type on intraocular pressure for lumbar surgery operations.

The effect of spinal and general anesthesia on intraocular pressure for lumbar discectomy surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12617001042336
Enrollment
10
Registered
2017-07-17
Start date
2017-03-01
Completion date
2017-08-30
Last updated
2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Prone position can increase intraocuar pressure especially for lumbar surgery. Many studies evaluated intraocular pressure in patients under general anesthesia. But there is not a study examinig patient under spinal anesthesia. In this study our aim is to investigate effects of spinal and general anesthesia on lumbar discectomy patients in prone position. 40 ASA I-III patients over 18 years old who undergo lumbar disc surgery patients will paritcipate study. Eye illness, eye surgery history, beta blocker drug usage, local anesthetic allergy are exclusion criterias. we record heigt, weight, hypertension or diabetes mellitus existence. We randomize patients in two groups. 1) Spinal anesthesia group 2) General anesthesia group We both measure intraocular pressure of both eyes each group when patients are supin position with portable tonometer. After that, we will perform spinal anesthesia with 15 mg hiperbaric bupivacaine from L3-4 lumbar interspace for spinal group and general anesthesia induction with fentanyl 2mcg/kg i.v., propofol 2 mg /kg i.v. and rocuronium 0.6 mg/kg for general anesthesia group patients and maintain anesthesia with 2% sevoflurane i.v.. We measure intraocular pressure after anesthesia at 10th minute, 10 minutes after prone positioning and at the end of the operation at prone position. We will record mean arterial pressure, at intraocular pressure measurements time, We will ask patients at first postoperative day if they have any visual disturbances. We compare the results of intraocular pressures and evaluate with appropriate statistical methods.

Interventions

Patients divided two groups. Anesthesia types are differnt for groups. 1. Group: Spinal anesthesia with 15 mg bupivacaine ( given to cerebrospinal fluid) before procedure. 2. Group General anesthesia with 2 mcg/kg fentanyl intravenous.,, 2 mg/kg propofol intravenous.and 0.6 mg / kg rocuronium intravenous induction doses, and anesthesia maintenance with 2 % sevoflurane inhalation until completion of procedure.

Sponsors

Baskent University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1) Patients > 18 years old 2) Patients who undergo lumbar discectomy surgery 3) ASA I-III physical status patients

Exclusion criteria

1) Patients who have any eye illness 2) Any operation from eyes 3) Beta blocker drug usage 4) Known local anesthetic allergy

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026