None listed
Conditions
Brief summary
Neurally Adjusted Ventilatory Assist (NAVA) is a new ventilatory technique in neonates to aid babies with respiratory distress. It uses the baby's diaphragmatic electrical activity as a trigger for each breath. This electrical activity is measured using a special nasogastric tube (Edi catheter) with electrodes at the level of the diaphragm. To date, there is a little data on the Edi signal in neonates with no existing respiratory conditions and on no respiratory support. By gaining a reference Edi data range, clinicians will be better equipped to titrate NAVA levels in ventilated neonates. We hypothesise that Edi peak and Edi min were higher in (1) Higher gestational age group, (2) awake and postprandial states and (3) after caffeine administration (caffeine is only administered to those infants using the medication as part of their hospital treatment).
Interventions
Neonates, with no existing respiratory conditions and no respiratory support, who have a nasogastric tube in-situ for feeding purposes will be enrolled in the study. When these neonates are due for a tube change, an appropriately sized Edi catheter will be inserted instead and used as a feeding tube. The catheter will be connected to a Servo-n ventilator and the Edi signal will be recorded for 4 hours which is the duration of the study. After 4 hours, the catheter will be disconnected from the v
Neonates, with no existing respiratory conditions and no respiratory support, who have a nasogastric tube in-situ for feeding purposes will be enrolled in the study. When these neonates are due for a tube change, an appropriately sized Edi catheter will be inserted instead and used as a feeding tube. The catheter will be connected to a Servo-n ventilator and the Edi signal will be recorded for 4 hours which is the duration of the study. After 4 hours, the catheter will be disconnected from the ventilator and used as a standard feeding tube. Intervention adherence will be assessed by participating researchers, research nurse and nurse educators through regular communication with data collector. The project will also be discussed during regular research meetings.
Sponsors
Srinivas Bolisetty
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
0 to 30 Days
Healthy volunteers
No
Inclusion criteria
Neonates of 29-42 gestation age, no respiratory support or existing respiratory conditions, nasogastric feeding tube in-situ, informed parental consent
Exclusion criteria
Known congenital anomalies, infants with respiratory distress, major neurologic conditions and brain anomalies, neuromuscular diseases, apneas, conditions affecting innervation of diaphragm
Outcome results
None listed