None listed
Conditions
Brief summary
This study aims to compare the Quality of life and Quality adjusted life years of surgical versus non-surgical Recurrent Rectal Cancer patients. Who is it for? You may be eligible to join this study if you are aged 18 years or above and have an isolated locally recurrent adenocarcinoma of the rectum or recto-sigmoid being considered for radical resection with or without perioperative chemoradiation. Study details If you choose to take part in this research, you will be asked to allow the investigators to access your disease related health information and will also be asked to complete questionnaires numerous times over five years. You will be asked about your demographics and quality of life at baseline; you will be asked about your quality of life at 3 months, 6 months, 12 months, 18 months, 24 months, 30 months, 36 months, 48 months, and 60 months. Conversely, if you choose not to take part in the study, the care provided to you will not be changed or prejudiced due to this decision; this is a purely voluntary study. There is no reimbursement for time or expenses. This study will provide important information about both the quality and quantity of the lifespan after diagnosis of Recurrent Rectal Cancer band thus could potentially assist in future treatment decisions.
Interventions
Surgical intervention. Half the participants will have surgical intervention for their recurrent rectal cancer. These patients will be followed up for five years or until death. On top of the surgery, they may receive chemotherapy and/or radiation. The decision to receive surgical intervention is made by the patient and their treating doctor, and is not a result of enrolling in this study (i.e. enrolment in this study results in no change to care because this is not a randomized controlled trial
Surgical intervention. Half the participants will have surgical intervention for their recurrent rectal cancer. These patients will be followed up for five years or until death. On top of the surgery, they may receive chemotherapy and/or radiation. The decision to receive surgical intervention is made by the patient and their treating doctor, and is not a result of enrolling in this study (i.e. enrolment in this study results in no change to care because this is not a randomized controlled trial).
Sponsors
University of Otago, Christchurch
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Those included for this study will: • have an isolated locally recurrent adenocarcinoma of the rectum or recto-sigmoid being considered for radical resection with or without perioperative chemoradiation. • be aged 18 years or older • be able to consent to participate.
Exclusion criteria
Those excluded will: • not have an adenocarcinoma • have primary (not recurrent) cancers • have non-resectable metastatic disease.
Outcome results
None listed