None listed
Conditions
Brief summary
The prevalence of gestation diabetes mellitus (GDM) is increasing worldwide, with current Australian prevalence rates estimated to be between 13-16%. Little is known about how to prevent GDM in high risk individuals. Strategies to date have largely focused on structured exercise programs. However, the results from these trials have shown little success possibly due to low adherence rates. Recently, studies suggest that sedentary behaviour during pregnancy is associated with increased risk for abnormal glucose tolerance, gestational diabetes and preeclampsia. This suggests that strategies that target a reduction in sedentary time could be an additional, or alternative approach to GDM prevention. However, before such interventions are developed, it is important to investigate the associations of objectively measured sedentary time and sleep patterns on blood glucose and GDM risk. This study aims to examine various descriptors of sedentary behaviour (total sedentary time, prolonged sedentary bouts, number of breaks in sitting) which will help to inform the design of early targeted sedentary behaviour interventions to reduce GDM incidence. Hypothesis: We hypothesise that measurement of sedentary time in pregnant women at 18-28 weeks gestation will be associated with higher fasting and post-challenge glucose levels during the screening test for GDM
Interventions
This is an observational study of sedentary behaviour and sleep patterns in pregnant women attending an outpatient maternity services clinic. Participation involves wearing two small lightweight devices (a sleep monitor and an activity monitor) for a period of 7 days in a 4-week window before the recommended oral glucose tolerance test to screen for gestational diabetes mellitus. The activity monitor (ActivPal) will be worn on the thigh and will provide information on times spent sitting, standi
This is an observational study of sedentary behaviour and sleep patterns in pregnant women attending an outpatient maternity services clinic. Participation involves wearing two small lightweight devices (a sleep monitor and an activity monitor) for a period of 7 days in a 4-week window before the recommended oral glucose tolerance test to screen for gestational diabetes mellitus. The activity monitor (ActivPal) will be worn on the thigh and will provide information on times spent sitting, standing and walking. The sleep monitor (Actigraph) will be worn on the wrist and will provide information on sleeping duration and sleep quality. Participants will choose the timing of the 7-day period within the 4-week window before their oral glucose tolerance test providing that the 7-day period is reflective of their normal weekly schedule.
Sponsors
Professor David Dunstan
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
This study will recruit pregnant, English-speaking women, aged 18-50 years at 18-27 weeks gestation.
Exclusion criteria
Criteria for exclusion include - >28 weeks gestation, multiple pregnancy, known diabetes, taking medications known to affect glucose metabolism, and current smokers.
Outcome results
None listed