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Joint mobilization of the hands in rheumatoid arthritis: an assessor-blinded, randomized crossover study

Joint mobilization of the hands as a potential method for reducing pain and improving ultrasound outcomes in patients with rheumatoid arthritis: an assessor-blinded, randomized crossover study

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12617000696392
Enrollment
20
Registered
2017-05-15
Start date
2015-02-27
Completion date
2016-12-14
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to assess the clinical applicability, safety and effectiveness of Kaltenborn manual mobilization of the hands in rheumatoid arthritis through affecting pain, tender/swollen joints, and musculoskeletal ultrasound outcomes; and to compare these findings across the treated and untreated hand; through crossover and follow-up; and through a clinical comparator group with hand osteoarthritis.

Interventions

Kaltenborn 'within-the-slack' Grade I-II manual mobilization is carried out in this study at the Rheumatology Clinic of the Karolinska University Hospital in Solna, Stockholm, Sweden, by five licensed Swedish manual therapists (1 physiotherapist, 4 naprapaths: minimum 1 year of experience) on the metacarpophalangeal (MCP) joints II-V of the hands of participants with rheumatoid arthritis (primary group) or hand osteoarthritis (clinical comparator group). Treatments are carried out individually p

Kaltenborn 'within-the-slack' Grade I-II manual mobilization is carried out in this study at the Rheumatology Clinic of the Karolinska University Hospital in Solna, Stockholm, Sweden, by five licensed Swedish manual therapists (1 physiotherapist, 4 naprapaths: minimum 1 year of experience) on the metacarpophalangeal (MCP) joints II-V of the hands of participants with rheumatoid arthritis (primary group) or hand osteoarthritis (clinical comparator group). Treatments are carried out individually per participant with two different therapists per hand. Kaltenborn Grade I-II manual mobilization is a method in manual therapy whereby the treated joint is gently mobilized with a traction force to reduce pain and help the joint regain functionality and flexibility. The method is utilized by manual therapists worldwide -- including physiotherapists, chiropractors, and naprapaths -- for treating joint- and muscle-related pain. In the context of this study, the session would begin with the participant sitting comfortably in front of a treatment table. One hand, relaxed from the support of a mobilization wedge or pillow, would face palm up. The therapist would then grip the proximal and intermediate phalanges of the finger with one hand whilst the other would grip the metacarpus for support; and then the joint (i.e. MCP II) would be mobilized with a gentle traction force. The process would be repeated for MCPs III-V. There is one treatment session per week with two sessions over two weeks per hand. First, the randomized hand of each participant is treated with 28-minute mobilization (per joint: 3min + 1min rest + 3min, MCP II-V) at baseline (week 1) and week 2. Upon crossover at week 3, the control hand is instead treated at week 3 and 4. An untreated 1-month follow-up after the final treatment (week 4) is carried out to assess outcome measures after a longer period without mobilization treatment.

Sponsors

Ronald van Vollenhoven
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Daily bilateral hand pain; diagnosis of rheumatoid arthritis or hand osteoarthritis at least six months prior to inclusion.

Exclusion criteria

Chronic bone damage or soft tissue injuries in the hands; acute hand inflammation within the latest week; surgery on the shoulder, arm, or hand within the latest 3 months of any kind; pregnancy within the latest 3 months.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026