The effect of local anesthetic infiltration to the nerves which lies on pectoral (chest) muscles on postoperative ( after operation) analgesia and opioid ( narcotic analgesics) consumption in aesthetic breast surgery operation.

The effect of pectoral nerve blocks on postoperative analgesia and opioid consumption in aesthetic breast surgery operation.

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12617000687392

Enrollment

Registered

2017-05-12

Start date

2017-05-15

Completion date

2018-04-30

Last updated

2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Using opioids for postoperative analgesia is a standard modality. But opioid related side effects like nausea-vomiting, respiratory depression, urinary retention, Pruritus limits its use. Peripheral nerve and truncus block with local anesthetics can improve postoperative analgesia and reduce opioid requirement. Our primary purpose in this study ; to investigate effect of pectoral nerve blocks on postoperative analgesia and total opioid consumption in aesthetic breast surgery operation.. We will take written informed consent for all patients before the procedure. We will record age, height, weight, American Society of Anesthesiologists (ASA) physical status of all patients.We will randomize patients into two group with computer program.In the operation room, we will routinely monitor electrocardiography, peripheric oxygen saturation and blood pressure.Standard anesthesia induction will perform for general anesthesia. At the end of breast surgery operation we will perform pectoral nerve blocks patients in intervention group. After skin disinfection first we will give 20 cc %0.25 bupivacaine fascia which lies between pectoralis minor and serratus anterior muscles between 3. and 4. ribs guided under ultrasound view. Then the same amount of bupivacaine will be given fascia which lies between pectoralis major and minor muscles. We will use appropriate needles for this intervention.It will take approximately 5 minutes. Both group ( control and intervebntion group) will take same postoperative analgesics routinely. Postoperative analgesia will provided with patient controlled analgesia (PCA) device which contains opioid drugs. Postoperative analgesia will measure with visual analog scale for pain and opioid consumption with PCA datas postoperative 0,1,2,4,6,8,12 and 24. hours .

Interventions

At the end of breast surgery operation anesthesiologists will perform pectoral nerve blocks patients in intervention group. After skin disinfection first anesthesiologists will give 20 ml %0.25 bupivacaine to fascia which lies between pectoralis minor and serratus anterior muscles between 3. and 4. ribs guided under ultrasound view. Then the same amount of bupivacaine will be given fascia which lies between pectoralis major and minor muscles. We will use appropriate needles for this interventi

Study design

Allocation

Randomised controlled trial

Primary purpose

Treatment

Masking

Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

1) Will undergo Aesthetic breast surgery operation 2)between 20-65 years old 3)American Society of Anesthesiologists (ASA) physical status I-II patients.

Exclusion criteria

1)antiepileptic drug use 2)Known allergy to study drugs 3)Severe renal or hepatic disease 4)Psychiatric disorders 5) Routine use of opioids or NSAI drugs 6)Pregnancy or lactation 7)Neurpathic disorders 8) Rejects study participation or using patient controlled analgesia device

Outcome results