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Evaluation of intensive risk factor modification in patients referred to a public clinic with chest pain.

In chest pain patients, does an intensive absolute cardiovascular risk guided risk factor management strategy (compared to usual care) improve subsequent cardiovascular risk

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12617000615381
Acronym
ARCPAC
Enrollment
221
Registered
2017-04-28
Start date
2014-07-01
Completion date
2017-12-19
Last updated
2020-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients referred to hospital chest pain clinics are often found to have non-cardiac (non threatening) symptoms, but have been found to have a high prevalence of risk factors (eg high cholesterol, smoking) for subsequent cardiovascular events (eg heart attack, stroke). These risk factors are not often formally addressed within a traditional chest pain clinic or cardiology clinic. The chest pain clinic provides an opportunity to identify patients at higher risk of subsequent cardiovascular events. We hypothesize that initiating strategies to modify individual risk factors during this initial visit will assist patients to develop a more favourable cardiovascular risk profile.

Interventions

Patients randomized to the intervention group will have a detailed discussion (with a cardiology nurse and treating cardiologist) regarding their cardiovascular risk, based on their 5-year risk calculation (using the Australian Absolute Risk Calculator - cvdcheck.org). This discussion will occur at the time of initial review at the Chest Pain Clinic, and is estimated to take around 40 minutes. The treating cardiologist will then develop an individualised risk management strategy in consultatio

Patients randomized to the intervention group will have a detailed discussion (with a cardiology nurse and treating cardiologist) regarding their cardiovascular risk, based on their 5-year risk calculation (using the Australian Absolute Risk Calculator - cvdcheck.org). This discussion will occur at the time of initial review at the Chest Pain Clinic, and is estimated to take around 40 minutes. The treating cardiologist will then develop an individualised risk management strategy in consultation with the patient, and communicated with their General Practitioner. The strategy will be based on the current recommendations of the National Heart Foundation Guidelines for management of cardiovascular risk. This may include lifestyle advice (exercise, dietary), prescription of lipid or blood pressure therapy where indicated, referral to the hospital's smoking cessation clinic +/- prescription of nicotine replacement therapy. Patients will be followed up via telephone (by a cardiology nurse) at 3, 6 and 9 month intervals, with in-person follow up at 12 months. At 12 months and five years, participants' absolute risk profile will be reassessed. Each contact point will provide an opportunity to monitor adherence to the agreed risk management strategy.

Sponsors

Royal Hobart Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

New patients referred to the chest pain service with uncomplicated chest pain suspicious of cardiac aetiology with intermediate to high baseline cardiovascular risk (>8% risk over 5 years)

Exclusion criteria

No prior cardiac history Pregnancy Subsequent primary cardiac diagnosis

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 16, 2026