None listed
Conditions
Brief summary
Endometriosis is the leading cause for pelvic pain in women and is also associated with infertility. Twenty percent of patients with endometriosis suffer from Deep Infiltrating Endometriosis (DIE), defined as solid endometriotic masses situated deep in the peritoneum. Laparoscopic surgery is a very common treatment for DIE, however, its implications on future pelvic organ function are not yet clear. The overall aim of our research is to investigate the influence of laparoscopic surgery for DIE on bowel, bladder and sexual function. We further aim to compare the effect of different surgical approaches on bowel and bladder function after bowel surgery for DIE. Our hypothesis is that extensive and radical surgery for DIE (such as bowel resection) will be found to be associated with long-term adverse bladder and bowel function and that less radical surgical approaches (such as bowel shaving) would be associated with lower rates of bladder and bowel dysfunction. The Royal Women’s Hospital is one of the largest women’s health institutes in Australia and is a major referral center for patients with pelvic pain and endometriosis. Patients will be recruited in the outpatients clinic and through the private rooms of the investigators in Frances Perry House and Epworth Richmond. Questionnaires will be filled before and at three points of time after surgery (6 weeks, 6 months, 1 year). Up to date, there is very scarce data regarding long term function after laparoscopic surgery for DIE and some of it is contradicting. This study intends to recruit a significant amount of patients in order to shed light on this question. The data collected in this study will allow us to better council patients before undergoing major surgery for DIE.
Interventions
Laproscopic surgery for Deep Infiltrating Endometriosis. This surgery includes excision of any endometriotic lesion across the pelvic side walls, uterine ligaments and ovaries. A minority of those cases include surgical treatment of bowel disease. This can be done by shaving or by resection. The duration of surgery for treatment of deep endometriosis without bowel involvement is 1.5-4 hours-depending on the severity of the disease. Duration of surgeries including bowel shaving is 3-4 hours, Duration of surgeries including bowel resection is 4-5 hours, Surgeries performed will be part of the usual care and no changes to patient's care are made as part of this study This study will compare pre and postoperative symptoms of patients who had surgery for treatment of Deep Infiltrating Endometriosis. Assessment of symptoms will be done by questionnaires that will be filled before and at three points of time after surgery (6 weeks, 6 months, 12 months).
Sponsors
Eligibility
Inclusion criteria
Pre-surgery: Age: 18-50 Pelvic pain and suspected pelvic endometriosis Planned laparoscopy for investigation and treatment of pelvic pain Patient agreement to participate in the study Post-surgery: Surgical evidence of deep infiltrating endometriosis Surgical treatment of deep infiltrating endometriosis Clear documentation of surgical findings in the operation report
Exclusion criteria
* Presence of co-morbidities affecting bladder and bowel function. * Women who do not consent. * Non-English speakers.