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Comparison of three approaches for primary Total Hip Arthroplasty

Comparison of outcome measures and complication rates following three different approaches for primary Total Hip Arthroplasty. A pragmatic randomised controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12617000272392
Enrollment
140
Registered
2017-02-22
Start date
2017-04-01
Completion date
2023-06-30
Last updated
2022-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a project analysing three surgical approaches for the same orthopaedic procedure, total hip arthroplasty (THA). This study will be conducted as a pragmatic randomised controlled trial comparing three approaches to the hip joint for this procedure – anterior, posterior and direct lateral (Hardinge) approaches. The null hypothesis is there will be no difference in outcomes between three approaches in terms of patient satisfaction with the procedure. We will measure this via validated scores: patient reported outcome measures (PROMs).

Interventions

Primary Total Hip Arthroplasty (THA) will be compared using three different surgical approaches. Anterior, Lateral and Posterior. Each approach has approximately the same surgical time of 90-120 minutes. Posterior Approach: This approach is the most common approach for THA worldwide today, made popular by Moore in 1959. This approach also allows excellent visualisation of the femoral shaft but involves detachment of the short external rotators of the hip with a posterior capsulotomy. Hardinge A

Primary Total Hip Arthroplasty (THA) will be compared using three different surgical approaches. Anterior, Lateral and Posterior. Each approach has approximately the same surgical time of 90-120 minutes. Posterior Approach: This approach is the most common approach for THA worldwide today, made popular by Moore in 1959. This approach also allows excellent visualisation of the femoral shaft but involves detachment of the short external rotators of the hip with a posterior capsulotomy. Hardinge Approach: This was first described by Hardinge in 1982. This approach requires the reflection of gluteus medius and minimus muscles off the greater trochanter. Anterior Approach: Initial description of this approach to the hip joint was by Smith-Petersen. It utilises the anatomic internervous plane between the superior gluteal nerve laterally and femoral nerve medially and has recently been popularised for THR, but it’s first reported use dates back to 1947 in France by Judet and colleagues. Patients will be randomised to surgical approach for THA. Each consultant surgeon will perform the approach which is their usual standard of care. Pre-operatively and post-operatively PROMs (OHS, VAS) will be taken at 6 weeks, 6, 12 and 24 months. Complications will be monitored, specifically dislocation, infection and revision.

Sponsors

Western Health
Lead SponsorOther

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Primary osteoarthritis of the hip requiring total hip replacement

Exclusion criteria

Prior bony procedures on hip Indication for THA is fracture, malignancy or developmental dysplasia

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 24, 2026