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Antimicrobial Resistance Patterns of Paediatric Urinary Tract Infections in South Australia

Antimicrobial resistance patterns in urinary isolates for optimization of empirical treatment of paediatric urinary tract infections

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12617000070336
Enrollment
642
Registered
2017-01-13
Start date
2015-08-01
Completion date
2016-05-31
Last updated
2017-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study is aimed at collating and analysing data of paediatric urinary tract infections, identifying antibiotic resistance patterns in different groups of children by age, gender, presence of renal tract abnormalities. It will also assessed the level of bacteraemia in younger children. The data will be used to evaluate whether current empiric antibiotics guidelines are adequate and suitable for all groups of patients and whether there is a need for new guidelines for high risk patients and younger patients.

Interventions

Urinary tract infection is a common bacterial infection in the paediatric population. It is an important cause of morbidity and mortality in children under 2 years of age. Increasing antibiotic resistance trends have important clinical implications for the empirical use of antibiotics. It is know that antimicrobial resistance vary according to geographic region. Knowledge of antimicrobial resistance patterns locally may aid clinicians in prescribing accurate empirical antibiotics treatment. Th

Urinary tract infection is a common bacterial infection in the paediatric population. It is an important cause of morbidity and mortality in children under 2 years of age. Increasing antibiotic resistance trends have important clinical implications for the empirical use of antibiotics. It is know that antimicrobial resistance vary according to geographic region. Knowledge of antimicrobial resistance patterns locally may aid clinicians in prescribing accurate empirical antibiotics treatment. This is a retrospective observational study is to examine antimicrobial resistance patterns in paediatric urinary tract infections in a single centre over the period of 12 months (1st April 2013 to 31st March 2014). Antimicrobial resistance patterns of patients with renal tract abnormalities were compared to those patients with normal renal tracts. All paediatric urine samples from 1st April 2013 to 31st March 2014 were reviewed. These samples were obtained from children who presented to the outpatient or emergency department; or who were admitted as inpatients. Urine samples that were collected by Paedibag (pediatric urine collection bag) and cottonball collection method were excluded. Cultures with mixed growth, and common contaminants were excluded. To prevent duplication, repeat samples within 30 days of first positive urine culture were excluded.

Sponsors

Dr Su Ling Chua
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years
Healthy volunteers
No

Inclusion criteria

1. Positive urine culture from patients ages 0 -18 years old. 2. Samples collected by suprapubic aspiration, catheterization and non-invasive collection sample (midstream) were include. 3. Only pure growth or predominantly pure growth samples were included. 4. Only the first positive urine sample of the encounter was included in the analysis to eliminate repetition.

Exclusion criteria

1. Positive urine culture within 30 days of the same patient were excluded to avoid repeat. 2. Pedibag (paediatric urinary bag) and cottonball collected samples were excluded. 3. Samples with mixed growth and common contaminants were excluded.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026