None listed
Conditions
Brief summary
The primary purpose of this study is to determine how the diagnosis of a bowel condition at colonoscopy/upper gastrointestinal condition at endoscopy, impacts quality of life, and whether this changes between diagnosis and one year later? We would also like to investigate the differences in the quality of life for those who have experienced surgery and/or neoadjuvant therapy, for colorectal, oesophageal or gastric cancer, within 3 years of treatment. Who is it for? Participants for this study will be people who have had a colonoscopy within the last two weeks, who have a diagnosis of one of the following at colonoscopy: (1) bowel cancer (stages I, II, III or IV), (2) advanced adenoma, (3) small non-advanced adenoma, (4) non-neoplastic findings (such as diverticular disease or haemorrhoids) or (5) no pathology detected (normal colon). People who have had an endoscopy within the last two weeks, who have a diagnosis for one of the following: (1) inflammation, (2) polyps, (3) oesophageal varices, (4) ulcers, (5) coeliac disease (6) Barrett’s oesophagus, (7) gastric cancer (stages I, II, III, IV), (8) oesophageal cancer (stages I, II, III, IV), or (9) no pathology detected, are also eligible. Also, for those who have had prior treatment for colorectal, oesophageal or gastric adenocarcinoma (stages I, II, III or IV) within the last 3 years. Study details: All study invitees will be sent via mail a study invitation letter and a questionnaire within two weeks after their colonoscopy appointment. The questionnaire contains questions about health conditions, health-related quality of life and well-being, attitudes toward managing health and other basic demographic questions (including age, education level and country of birth). A two week period will be allowed following the mail out of letters for return of completed questionnaires. If the questionnaire has not been returned during this time, then research staff will make telephone contact with the study invitees to follow-up and confirm their willingness or otherwise to participate in the study. Those who complete the questionnaire will be invited to complete the same questionnaire 12 months later. Individuals who have had prior treatment for colorectal, oesophageal or gastric cancer, within 3 years, will be sent the same information, an invitation letter, participant information sheet and consent and a once-only questionnaire. Follow-up telephone contact will also be initiated, should there be no response after two weeks. The invitees are given the option to withdraw from the offer of participation by telephone or withdrawal form, at any time. It is hoped that the findings of this trial will provide health related quality of life data for different bowel and upper gastrointestinal conditions and experiences in the Australian population. This can then be used in health economic modelling to assess the cost effectiveness of bowel cancer screening.
Interventions
People aged 40 or older and who have had a recent diagnosis of a bowel condition at colonoscopy will be contacted about this study. This will include people with a main diagnosis of a small adenoma, a significant adenoma, bowel cancer of stage I, II, III or IV, or those with non-neoplastic findings such as diverticular disease or haemorrhoids. People aged 40 or older and who have had a recent diagnosis of a upper gastrointestinal condition at endoscopy will also be contacted about this study. Th
People aged 40 or older and who have had a recent diagnosis of a bowel condition at colonoscopy will be contacted about this study. This will include people with a main diagnosis of a small adenoma, a significant adenoma, bowel cancer of stage I, II, III or IV, or those with non-neoplastic findings such as diverticular disease or haemorrhoids. People aged 40 or older and who have had a recent diagnosis of a upper gastrointestinal condition at endoscopy will also be contacted about this study. This will include people with gastric or oesophageal cancer of stage I, II, III or IV, or those with non-neoplastic findings such as inflammation, polyps, Barrett’s oesophagus, varices, ulcers, coeliac disease or normal endoscopy. Within two weeks after colonoscopy or endoscopy, people will be sent a letter inviting them to take part in a questionnaire at this time point and again 12 months later. The questionnaire contains four sections. Section A mainly includes questions about health conditions and any treatment that the person may have received in the past 12 months. Section B contains questions about health-related quality of life and wellbeing. Section C contains questions on attitudes towards managing health. Section D includes questions about the person's background. If the questionnaire is not returned within two weeks then research staff will make telephone contact with the invitees to follow-up and confirm their willingness or otherwise to participate in the study. Another sub-group of participants will now be included in this study, to capture more information about the quality of life (QOL) from individuals who have completed treatment for colorectal adenocarcinoma, gastric adenocarcinoma or oesophageal adenocarcinoma (stages I, II, III, IV). A single questionnaire will be offered to these individuals who are within 3 years post-surgery/neoadjuvant therapy.
Sponsors
Erin Symonds
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
-Recent colonoscopy (within two weeks) where one of the following new diagnoses are made: colorectal cancer, advanced adenoma, non-advanced adenoma, no neoplasia but other pathology (such as diverticular disease, haemorrhoids), normal colonoscopy -Recent endoscopy where one of the following new diagnoses were made: gastric cancer, oesophageal cancer, inflammation, polyps, Barrett’s oesophagus, varices, ulcers, coeliac disease, normal endoscopy. -Aged 40 years or older -Be able to read and write in English -History of colorectal cancer treatment within the last 3 years
Exclusion criteria
-Currently has another type of cancer -Has a pre-existing and ongoing bowel condition that requires medication or is the indication for the colonoscopy, eg. inflammatory bowel disease
Outcome results
None listed