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Electroencephalography (EEG) Biofeedback Training to Improve Memory for People with a Mild Memory Deficit

Source Localised EEG Biofeedback of the Posterior Cingulate Cortex to Improve Immediate Memory Scores in People with Mild Memory Deficit

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616001731482
Enrollment
53
Registered
2016-12-16
Start date
2016-01-15
Completion date
2016-11-17
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

EEG biofeedback is a form of brain training where we take recordings of brain activity from the scalp, analyse the data for specific patterns from a specific part of the brain called th Posterior Cingulate Cortex, and display it graphically on a computer screen. Participants then use their own willpower to alter their brain activity. It is a non-invasive and safe procedure to undergo. We are aiming to recruit people with a mild memory deficit to see whether we can change these rhythms, in order to improve their memory function on objective testing.

Interventions

15 sessions of source localised EEG biofeedback, using sLORETA, of the posterior Cingulate Cortex, designed to train up theta and alpha band frequencies, and decrease beta band frequencies. At each session, a 21 electrode EEG cap is worn by the participants, which includes 2 reference ear electrodes and a ground electrode. The 19 remaining channels produce an EEG montage referenced to the average on a laptop computer. The current density of the relevant frequency bands is calculated in real time

15 sessions of source localised EEG biofeedback, using sLORETA, of the posterior Cingulate Cortex, designed to train up theta and alpha band frequencies, and decrease beta band frequencies. At each session, a 21 electrode EEG cap is worn by the participants, which includes 2 reference ear electrodes and a ground electrode. The 19 remaining channels produce an EEG montage referenced to the average on a laptop computer. The current density of the relevant frequency bands is calculated in real time over a four second interval, and the result displayed to the participant as the height of a vertical bar on the screen. The participant is then asked to try and keep the bar in the top half of the screen as much as possible. Each session has 30 minutes of active training with 1 minute relaxation at 5 mintues intervals thoughout. Participants complete a maximum of three and a minimum of 2 sessions a week, until they have completed 15 sessions. 15 sessions of source localised EEG biofeedback, using sLORETA, of the posterior Cingulate Cortex, designed to train up alpha band frequencies, and decrease beta band frequencies. At each session, a 21 electrode EEG cap is worn by the participants, which includes 2 reference ear electrodes and a ground electrode. The 19 remaining channels produce an EEG montage referenced to the average on a laptop computer. The current density of the relevant frequency bands is calculated in real time over a four second interval, and the result displayed to the participant as the height of a vertical bar on the screen. The participant is then asked to try and keep the bar in the top half of the screen as much as possible. Each session has 30 minutes of active training with 1 minute relaxation at 5 mintues intervals thoughout. Participants complete a maximum of three and a minimum of 2 sessions a week, until they have completed 15 sessions. All sessions in all groups are carried out at Dunedin Hospital, supervised by a PhD student.

Sponsors

University of Otago, Dunedin School of Medicine
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject)

Eligibility

Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Score below 90 on the immediate memory index of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)

Exclusion criteria

Participants must be free of significant neurological or psychiatric disease. Mild depression or anxiety is permitted. Participants who score below 21/30 on the Mini Mental State Examination are excluded from the study

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026