Correlation of peripheral venous collapse with central venous pressure as a non-invasive bedside clinical sign

Correlation of peripheral venous collapse with invasively monitored central venous pressure. A single centre prospective observational study

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12616001683426

Enrollment

Registered

2016-12-07

Start date

2016-12-08

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to determine whether there is a correlation between the height at which the veins on the back of the hand collapse, and the pressure measured by a central venous catheter in the heart (central venous pressure).The central venous pressure is used to guide how much fluid should be given to a patient, but is currently only available using invasive procedures performed in special departments within hospitals, such as intensive care. It would therefore be very helpful to be able to obtain this pressure using a non-invasive technique that could be used anywhere. This study will be performed on patients in intensive care with a central venous catheter already in place as part of their treatment. After the participant has provided consent, the head of the bed will be positioned at a slight angle (45 degrees), and the participant assisted to slowly raise their arm above the level of their chest. The veins on the back of the hand will be observed as the arm rises, and the height at which the veins collapse will be recorded. At the same time, the pressure reading via the central venous catheter that is constantly displayed on the monitor will be noted. The total time required should not be more than 15 minutes. A biostatistician will then analyse the readings to determine if there is correlation between the two measurements in each participant. There are no additional risks to participants in this study. All the risks associated with this study are related to use of the central venous catheter, which will already be present as part of their standard care.

Interventions

The height of peripheral venous collapse will be compared with the invasively monitored central venous pressure in a cohort of spontaneously breathing intensive care patients. This study will be performed on patients in intensive care with a central venous catheter already in place as part of their treatment. After the participant has provided consent, the head of the bed will be positioned at a slight angle (45 degrees), and the participant assisted to slowly raise their arm above the level of their chest. The height of peripheral venous collapse will be observed by observing the veins on the back of the hand as the arm rises, and the height at which the veins collapse will be recorded. At the same time, the pressure reading via the central venous catheter that is constantly displayed on the monitor will be noted by a separate observer. A single assessment will be performed; the total time required should be no more than 5-10 minutes.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ICU patients * Age greater than or equal to 18 years * Able to provide consent * Visible vein on the dorsal aspect of the hand * Current central venous pressure monitoring via central venous catheter

Exclusion criteria

* Management with vasoactive infusions * Invasive or non-invasive mechanical ventilation * Medical contraindication to arm-raising * Deemed unsuitable by treating intensive care unit doctor

Outcome results