None listed
Conditions
Brief summary
The primary purpose of this trial is to evaluate whether treatment planning for prostate cancer radiotherapy can be completed using only MRI scans, in place of the standard care which involves both MRI and CT scans. Who is it for? You may be eligible to participate in this study if you are aged over 18 years and have been diagnosed with prostate cancer for which you are scheduled to undergo radiotherapy treatment. Study details All participants enrolled in this trial will have the standard care CT scan and MRI scan performed as part of their radiotherapy treatment planning, with an extra type of MRI scan added on to the existing MRI. This will add approximately six minutes to the duration of the MRI scan. A team of doctors, physicists and radiation therapists will work together to generate two treatment plans (CT plan and MRI plan). If the treatment plans are similar then the new MRI only treatment plan will be used for treatment. If the two treatment plans differ then the standard care CT and MRI plan will be used for treatment. Researchers will keep track of the number of times that the new MRI only treatment plan is used, the doses calculated and the locations of any gold markers used. It is hoped that the findings of this trial will provide information on whether radiotherapy treatment planning for prostate cancer can be completed using only MRI scans, without the need for CT scans. This would reduce the time and cost required for radiotherapy treatment planning in these patients.
Interventions
1) Additional T2 weighted MRI sequence added to patients routine MRI scanning session. This is performed once during radiation treatment planning. It will add approximately 6 minutes to the total scanning time. MRI's will be performed at Calvary Mater Newcastle. 2) Technical modification of radiation treatment planning workflow. This intervention will be provided by Clinicians, Physicists and Radiation Therapists who collaborate to plan radiation treatment for prostate cancer patients. The mai
1) Additional T2 weighted MRI sequence added to patients routine MRI scanning session. This is performed once during radiation treatment planning. It will add approximately 6 minutes to the total scanning time. MRI's will be performed at Calvary Mater Newcastle. 2) Technical modification of radiation treatment planning workflow. This intervention will be provided by Clinicians, Physicists and Radiation Therapists who collaborate to plan radiation treatment for prostate cancer patients. The main differences in workflow will be: A substitute CT scan will be generated, A substitute CT scan is an artificially created CT scan produced from the MRI scan data. QA procedures will be used to confirm that the substitute CT scan dose calculation is accurate, A comparison of the substitute CT scan dose calculation with the conventional CT scan dose calculation, A comparison of marker locations on substitute CT and conventional CT scans for treatment guidance.
Sponsors
Calvary Mater Newcastle
Study design
Allocation
Non-randomised trial
Primary purpose
Treatment
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Men diagnosed with prostate cancer deemed suitable for radiation treatment
Exclusion criteria
Unsuitable for radiotherapy including inability to have MRI scans or gold markers inserted, previous pelvic radiotherapy, hip prosthesis.
Outcome results
None listed