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Effects of combined cognitive-exercise program in older adults with mild cognitive impairment

Effects of combined cognitive-exercise program on cognitive function and functional status in older adults with mild cognitive impairment

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616001635459
Enrollment
145
Registered
2016-11-25
Start date
2017-05-02
Completion date
2018-10-20
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The main aim of this study is to validate the early findings whether a combined cognitive and exercise programme is effective in improving the cognitive functions of older individuals with mild cognitive impairment. A further aim is to assess whether participation in a combined cognitive and exercise programme can reduce functional decline and increase quality of life in older individuals with mild cognitive impairment and their carers.

Interventions

8-week (group of 4-6; 3 sessions per week, 1 hour per session), center-initiated home based functional task exercise program. For the first 4 weeks, center-based sessions will be scheduled twice weekly supported with once weekly home practice with caregiver, followed by once weekly center-based and twice weekly home practice session for 4 weeks. The intervention program will be conducted by occupational therapist. Physical parameters associated with balance, strength, flexibility, mobility will

8-week (group of 4-6; 3 sessions per week, 1 hour per session), center-initiated home based functional task exercise program. For the first 4 weeks, center-based sessions will be scheduled twice weekly supported with once weekly home practice with caregiver, followed by once weekly center-based and twice weekly home practice session for 4 weeks. The intervention program will be conducted by occupational therapist. Physical parameters associated with balance, strength, flexibility, mobility will be incorporated to daily functional task. All exercise sessions will begin with a 5-10 minutes warm-up consisting of light stretching designed to increase flexibility, 30-40 minutes core exercise and end with a 5-10 minutes cool-down. The core exercise includes simulated functional task (table task of placing and collection with five levels and combined with chair rise exercise) will be used according to the training protocol and training guidelines. Compliance/ Intervention Monitor: Attendance for center-based sessions will be registered and home exercise log will be recorded by participants and followed up during each first supervised session in the week.

Sponsors

Tung Wah College
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1) Memory/cognitive complaint; (2) Objective cognitive impairment in 1 or more domains (Cognistat); but with (3) intact personal selfcare functions; (4) Absence of Dementia

Exclusion criteria

(1) History of brain lesion/ psychoactive substance abuse/co-morbid medical condition associated with cognitive/ functional decline; (2) Clinically significant depression; (3) significant impairment of vision, hearing or communication(4) Medical conditions render patients unable to engage in physical activity, such as severe cardiac failure

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026