None listed
Conditions
Brief summary
Current evidence suggests exercise plays an important role in the management of blood glucose levels for individuals with T2DM.The comparison on mode of exercise on glucose regulation is not well understood and limited. Previous research have investigated treadmill or cycling exercise on glucose tolerance separately, however the comparison between the two modes of exercise on glucose regulation is limited. We seek to determine which mode of exercise would be more effective in managing glucose tolerance since walking/running is freely accessible without having the need to sign up to a gym or to invest in a bicycle. It is now understood that type 2 diabetes is associated with a chronic state of inflammation. Recent evidence have shown that exercise is beneficial in improving inflammation along with reducing insulin resistance. We aim to identify whether the mode of exercise influences the level of inflammation and glucose tolerance following a two-week training period. Findings of this study may help inform future exercise prescription to improving health status in this population.
Interventions
Participants will be randomised into an exercise group of either treadmill or cycle exercise.
Exercise will last for 45 minutes (moderate intensity at 65% of VO2peak) and will last for 10 sessions over a two-week period at the Murdoch University exercise physiology laboratory.
An oral glucose tolerance test will be completed pre and post-training with blood samples taken every 30 minutes. Blood samples will also be used to measure immune related cells such as regulatory T cells.
Familiarisat
Participants will be randomised into an exercise group of either treadmill or cycle exercise. Exercise will last for 45 minutes (moderate intensity at 65% of VO2peak) and will last for 10 sessions over a two-week period at the Murdoch University exercise physiology laboratory. An oral glucose tolerance test will be completed pre and post-training with blood samples taken every 30 minutes. Blood samples will also be used to measure immune related cells such as regulatory T cells. Familiarisation will preceed training with a VO2peak test, body composition analysis and anthropometrics measured. Exercise will be supervised by the PhD student who is running the project.
Sponsors
Murdoch University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
Diagnosed as type 2 diabetic, BMI > 27 Sedentary or low level of physical activity (1 or 2 bouts per week)
Exclusion criteria
Non-diabetic, healthy and active individuals. BMI < 27
Outcome results
None listed