A Retrospective Review of Intra-operative Anaesthesia Management during Fractured Neck of Femur (IAM-NOF) Surgery and Mortality

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12616001472460

Acronym

IAM-NOF

Enrollment

1008

Registered

2016-10-24

Start date

2017-02-01

Completion date

2018-06-11

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a retrospective study of the influence of intra-operative blood pressure management and depth of anaesthesia on mortality after fractured neck of femur (NOF) surgery. Hospital admission and surgery for hip fractures is very common, and is associated with a high mortality rate. To date, finding anaesthesia interventions which could influence mortality has been unsuccessful. This study will review the medical, surgical, and anaesthesia records of patients admitted for NOF surgery in a 4 year period (2012 – 2016) in Liverpool Hospital. Relevant anaesthesia data, such as blood pressure pre- and intra-operatively, as well as depth of anaesthesia levels, will be collected. NOF patients will be identified through the Department of Orthopaedics database of surgical operations records for the same period. This also records 30- and 120-day mortality. This will allow researchers to analyse the impact of anaesthesia management on post-operative mortality.

Interventions

This is a retrospective study of the influence of intra-operative blood pressure management and depth of anaesthesia on mortality after fractured neck of femur (NOF) surgery. This study will review the medical, surgical, and anaesthesia records of patients admitted for NOF surgery in a 4 year period (2012 – 2016) in Liverpool Hospital. Relevant anaesthesia data, such as blood pressure pre- and intra-operatively, as well as depth of anaesthesia levels, will be collected. NOF patients will be identified through the Department of Orthopaedics database of surgical operations records for the same period. The database records 30- and 120-day mortality. The data from both medical records and the NOF database will be cross-referenced and combined, to allow researchers to analyse the impact of anaesthesia management on post-operative mortality.

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

Adult patients, >50 years old, admitted for emergency fractured NOF surgery in the 4 year time period, June 01 2012 - June 30, 2016

Exclusion criteria

Patients admitted for NOF but not offered surgery

Outcome results