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Effect of attention bias modification (ABM) on chronic pain and associated health outcomes in Defence personnel

Effect of attention bias modification (ABM) on pain-related attention biases, mental health and well-being in Defence personnel

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616001460493
Enrollment
69
Registered
2016-10-19
Start date
2016-10-25
Completion date
2018-11-06
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Pain confers a survival advantage by drawing our attention to injury. Yet this attention bias towards pain-related cues can become maladaptive in people with chronic pain. Importantly, the direction of attention can be modified using a method known as attention bias modification (ABM). Preliminary research suggests this approach may be effective for the treatment of chronic pain. This is the first study to examine its effectiveness in a military population. This study aims to determine whether multiple sessions of an ABM using pain cues will reduce attention bias to pain cues, reduce pain severity and related disability (e.g., pain interference) and improve mental health in ADF members with chronic pain. The study will be a parallel-groups randomized superiority trial comparing 5 sessions of ABM (using pain-related word cue attention modification training via a modified dot-probe task) versus sham training (i.e., placebo control condition, via a dot-probe task) in 100 Defence personnel who self-report chronic pain experience lasting at least 3 months. 100 Australian Defence Force members who report chronic pain (persisting at least 3 months) will be recruited and randomly allocated to undergo either ABM training or sham training (placebo control comparison). Pre- and post-intervention attention biases will be assessed via a computerised task (<10 mins) where reaction times for different categories of pain words will be measured. At each of the five training sessions, participants in the intervention group will undergo a modified version of this computerised task (< 10 mins) which implicitly trains participants to direct their attention away from these target cues. Control group participants will complete an equivalent task without the training contingencies. Questionnaires assessing demographic and key outcome variables will be completed via an online survey prior to the first training session (baseline) and at 1-month follow-up. During the 5-week intervention period, a brief (5-10 mins) online survey will be completed the next day following each training session to assess incremental changes in mood and pain ratings.

Interventions

This study aims to determine whether multiple sessions of an ABM using pain cues will reduce attention bias to pain cues, reduce pain severity and related disability (e.g., pain interference) and improve mental health in ADF members (serving and ex-serving) with chronic pain. The study will be a parallel-groups randomized superiority trial comparing 5 sessions of ABM (using pain-related word cue attention modification training via a modified dot-probe task) versus sham training (i.e., placebo co

This study aims to determine whether multiple sessions of an ABM using pain cues will reduce attention bias to pain cues, reduce pain severity and related disability (e.g., pain interference) and improve mental health in ADF members (serving and ex-serving) with chronic pain. The study will be a parallel-groups randomized superiority trial comparing 5 sessions of ABM (using pain-related word cue attention modification training via a modified dot-probe task) versus sham training (i.e., placebo control condition, via a dot-probe task) in Defence personnel who self-report chronic pain experience lasting at least 3 months. The 2 arms include: 1. Behavioural: Attention bias modification (ABM) treatment Attention training using a computerized spatial attention task (dot-probe, DPT) modified to alter pain-related attention patterns using pain and neutral stimuli (with the probe placed in the opposite location to the pain stimuli). 2. Behavioural: Sham ABM placebo control condition Attention training using a computerized spatial attention task (dot-probe) not intended to alter pain-related attention patterns using the same pain and neutral stimuli (with the probe replacing the pain vs. neutral stimuli equally often). Stage 1: Participants will complete a series of online (or hard-copy option upon request) validated questionnaires to assess baseline (and at post-intervention) levels of key outcome and demographic variables. Participants will then be randomised to receive double-blinded administration of either ABM or sham (placebo control) training. Stage 2: Participants attend 1 training session a week for 5 weeks (of ABM or sham training). Prior to the first training session and at the completion of the final training session, pre- and post-intervention attention biases will be assessed, respectively, via a computerised visual probe task (<10 mins) where reaction times for different categories of pain words related to sensory and affective experiences will be measured. Participants are randomly allocated to receive either ABM or sham training, taking approximately 10 minutes each session (n = 50 each). *ABM, ‘away pain’ – in this condition, participants’ attention is implicitly re-directed away from pain-related cues (compared to neutral cues). This occurs via the placement of the dot probe in the opposite location of the pain cue on all trials. *Sham ABM control – participants’ attention is not trained toward or away from any stimuli type in this condition (i.e., similar to the assessment task, with the location of the dot probe replacing the pain cues 50% of the time). This condition serves as a placebo control group. During the 5-week intervention period, a brief (5-10 min) online survey will be completed the day following each training session to assess incremental changes in mood and pain ratings. Stage 3: Online questionnaires (or hard copy upon request) will be administered immediately and at 1-month following the final training session to assess acute and sustained or delayed effects on key clinical outcome variables (e.g., pain, disability, negative affect). Session 1 includes pre-intervention DPT assessment prior to ABM trials (20 min). Sessions 2-4 include only ABM trials (10 min). Session 5 includes post-intervention DPT assessment following the ABM trials (20 min). Each session includes instruction screens and practice trials using neutral stimuli. The interventions are delivered face-to-face by trained research assistants (with postgraduate psychology qualifications) via the experiment presentation software, E-prime 2.0, on laptop computers at a workstation (individual testing) in an office space or consulting room at the participant's local Defence base (e.g., local Barracks office space), local ex-service organisation, public library meeting room, or in a quiet room at one of the QUT campuses. All participant instructions for performing the dot probe task are contained within the program, such that the participant can read these at their own pace, pause to ask any questions of the research assistant before proceeding from the practice block to the intervention or assessment block.

Sponsors

Queensland University of Technology (QUT)
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Aged 18 years or older, currently serving or ex-serving Defence member, have been experiencing pain for at least 3 months, and had this pain experience in the last few months

Exclusion criteria

No exclusion criteria. Participants are only required to meet the inclusion criteria.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026