The demographic factors associated with blood ketone levels in acute care patients.

An observational study of the demographic factors, blood chemistry and clinical observations associated with blood ketone levels in acute care patients during hospital admission.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12616001457437

Enrollment

Registered

2016-10-19

Start date

2017-06-14

Completion date

2019-12-31

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Blood ketone measurement has been used in the treatment of diabetic ketoacidosis for some time. However it also provides a monitor of nutritional status. Ketonaemia [elevated blood ketones] occur when the body switches from glucose to fatty acids as the main metabolic substrate. This occurs in starvation, during illness and also with prolonged perioperative fasting. The aim of this study is to establish the prevalence and associations of ketonaemia in acute care patients. Point of care, single drop, blood analysis [similar to blood sugar testing] provides a simple method of detecting ketonaemia. Making measurements on discarded blood during cannulation or routine blood collection and relating the ketone level to factors collected from the electronic medical record [eMR] will enable normal ranges and demographic associations to be established. This observational study will permit use of blood ketone measurement to detect nutritionally vulnerable populations and establish a baseline for studies of specific interventions in the future.

Interventions

A single blood ketone level will be measured using a drop of blood discarded during cannulation or incidental to other blood tests during acute inpatient care.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients attending hospital for acute inpatient care. They will be a sample of convenience selected from surgical, intensive care and emergency department attendances.

Exclusion criteria

Patients that are not already having blood tests or cannulation.

Outcome results