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The effect of oral fluid intake on volume depletion in patients having a colonoscopy.

The effect of oral fluid intake during the immediate pre-colonscopy time period on volume depletion in patients who receive sodium picosulfate.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616001300460
Enrollment
392
Registered
2016-09-16
Start date
2012-04-01
Completion date
2015-05-01
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This project aims to test whether enhanced fluid intake on the morning of a colonoscopy can avoid some of the deleterious effects associated with bowel preparation and prolonged fasting. It will examine whether increased fluid intake of up to 1,200 mls of Gatorade during the morning, up to 2.5 hours before the start of the afternoon list will alter the incidence of fluid depletion and dehydration, and the associated symptoms and clinical signs such as headache, dry moth, thirst, dizziness, postural hypotension and concentrated urine. This will be compared to a control group fasting from 0600 on the day of the procedure.

Interventions

Encourage oral hydration up to 2.5 hours before commencement of afternoon colonoscopy list. This is done by offering two 600 ml bottles of Gatorade at the pre-anaesthesia consultation along with written instructions for their use on the day of the procedure. Each 600 ml bottle contains 36g sugars, 13.7 mmol sodium and 3.6 mmol potassium. The written instructions explained that the drink was to be consumed between 0700 and arrival at hospital on the day of the procedure around 1100. Participa

Encourage oral hydration up to 2.5 hours before commencement of afternoon colonoscopy list. This is done by offering two 600 ml bottles of Gatorade at the pre-anaesthesia consultation along with written instructions for their use on the day of the procedure. Each 600 ml bottle contains 36g sugars, 13.7 mmol sodium and 3.6 mmol potassium. The written instructions explained that the drink was to be consumed between 0700 and arrival at hospital on the day of the procedure around 1100. Participants were asked what actual volume they had consumed in the recovery room after the procedure.

Sponsors

Department of Anaesthesia, St. George Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients attending pre-admission clinic that are scheduled for afternoon colonoscopy. They will all receive a sodium picosulphate bowel prep on the day prior to the procedure.

Exclusion criteria

uncontrolled congestive cardiac failure, haemodynamic instability, bowel obstruction, renal failure on fluid restriction, hospitalised patients, emergency cases, non-English speaking and those with intellectual disabilities.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026