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Noninvasive brain stimulation and it's effects on balance and proprioception in Parkinson's disease

Combining high definition transcranial direct current stimulation with motor training and it's effects on early to midstages Parkinson's Disease symptoms

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616001105437
Enrollment
14
Registered
2016-08-16
Start date
2015-07-13
Completion date
2016-10-28
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study uses high definition, noninvasive, transcranial direct current stimulation in combination with exercises in balance and proprioception. We aim to improve performance on balance and proprioception tests in people with Parkinson's disease. As a result, we aim to see an increase in quality of life and a decrease in the risk of falls.

Interventions

High definition transcranial direct current stimulation (HD tDCS) + Proprioceptive training. 15 minutes of active anodal stimulation at 1.5mA over the motor cortex, directly followed by 30 minutes of proprioceptive and balance training. These sessions will be run 3 times a week for 4 weeks. The exercises were novel, developed by a team of specialist physiotherapists and based on daily household activities like reaching. The stimulation and exercises were delivered by the primary investigator, a

High definition transcranial direct current stimulation (HD tDCS) + Proprioceptive training. 15 minutes of active anodal stimulation at 1.5mA over the motor cortex, directly followed by 30 minutes of proprioceptive and balance training. These sessions will be run 3 times a week for 4 weeks. The exercises were novel, developed by a team of specialist physiotherapists and based on daily household activities like reaching. The stimulation and exercises were delivered by the primary investigator, a PhD candidate in the Faculty of Health with a background in neuroscience. All sessions in this intervention are one-on-one and take place in a laboratory setting at the University of Canberra. The study runs for 8 weeks, with three sessions of stimulation/exercise per week, and one fortnightly baseline measures session. The wash out period is two weeks, this does not have to be longer due none of the treatments being continued across both sessions and progress can be compared to baseline measures taken before interventions.

Sponsors

University of Canberra
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Diagnosis of Parkinson's Disease by a neurologist, over 40 years of age at diagnosis, able to walk independently (with stick or a frame accepted),

Exclusion criteria

Early onset Parkinson's, late stages Parkinson's, atypical Parkinson's, history of other neurological disease/s, history of severe ankle injury.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026