None listed
Conditions
Brief summary
The purpose of this study is to determine if consumption of two gold kiwifruit per day for 12 weeks favourably alters gut microbiota composition without adversely affecting blood glucose control in people with pre-diabetes..
Interventions
All participants will be asked to consume 2 gold kiwifruit (flesh only) with their breakfast every day for 12 weeks. Adherence will be monitored by food diaries and by measurement of vitamin c in blood samples.
Sponsors
University of Otago
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Inclusion criteria: Selection criteria for trial participants will be the requirement to meet the diagnostic criteria for prediabetes according to the American Diabetes Association (ADA) criteria for glycated haemoglobin (HbA1c). All participants will be free living and required to maintain their normal dietary and lifestyle habits for the duration of the trial. ADA criteria for the diagnosis of prediabetes: HbA1c: 39-46 mmol/mol inclusive.
Exclusion criteria
Exclusion criteria: a.Individuals unable to give informed consent. b. Those with an HbA1c outside the range of 39-46 mmol/mol. c. Those with a previous diagnosis of diabetes. d. Those on diabetes medications such as Metformin. e.Those that have taken antibiotics within a month prior to the trial starting. f.Those with a known kiwifruit allergy. g.Those with a medical history of significant gastrointestinal disease for example, coeliac disease, inflammatory bowel disease or a previous bowel resection. h.Women who are pregnant, breastfeeding or planning a pregnancy in the 3 months post selection (trial period) will be excluded. i.Those who have a planned trip overseas in the 3 months post selection will be excluded.
Outcome results
None listed