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Lymphadenectomy for Pancreatic Head Cancer: Standard or Extended?

A Prospective Randomized Controlled Study Comparing Standard and Extended Lymphadenectomy for Pancreatic Head Cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616000854437
Enrollment
89
Registered
2016-06-29
Start date
2016-06-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to compare outcomes of patients undergoing standard or extended lymphadenectomy in pancreaticoduodenectomy for pancreatic ductal adenocarcinoma

Interventions

Pancreaticoduodenectomy for Pancreatic ductal adenocarcinoma with standard or extended lymphadenectomy undergoing by the surgeons from Ruijin Hospital standard lymphadenectomy includes standard lymphadenectomy and No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b lymph nodes stations extended lymphadenectomy includes No8p 12a 12p 14c 14d 16 lymph nodes stations and those in standard lymphadenectomy( No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b) The details of all lymph nodes stations are descr

Pancreaticoduodenectomy for Pancreatic ductal adenocarcinoma with standard or extended lymphadenectomy undergoing by the surgeons from Ruijin Hospital standard lymphadenectomy includes standard lymphadenectomy and No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b lymph nodes stations extended lymphadenectomy includes No8p 12a 12p 14c 14d 16 lymph nodes stations and those in standard lymphadenectomy( No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b) The details of all lymph nodes stations are described as below: No. 5, Suprapyloric lymph nodes; No. 6, infrapyloric lymph nodes; No. 8a, lymph nodes in the anterosuperior group along the common hepatic artery; No. 8p, lymph nodes in the posterior group along the common hepatic artery; No. 12a, lymph nodes along the hepatic artery; No. 12p, lymph nodes along the portal vein; No. 12b, lymph nodes along the bile duct; No. 12c (located next to 12b), lymph nodes around the cystic duct; No. 13a, lymph nodes on the posterior aspect of the superior portion of the head of the pancreas; No. 13b, lymph nodes on the posterior aspect of the inferior portion of the head of the pancreas; No. 14, lymph nodes along the superior mesenteric artery (a & b. right lateral side, c & d. left lateral side ); No. 16, lymph nodes around the abdominal aorta;.No. 17a, lymph nodes on the anterior surface of the superior portion of the head of the pancreas; No. 17b, lymph nodes on the anterior surface of the inferior portion of the head of the pancreas

Sponsors

Shanghai Ruijin Pancreatic Disease Center
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

1. Pathologic diagnosis of pancreatic ductal adenocarcinoma 2. Signed the informed consents

Exclusion criteria

1. Pathologic diagnosis of other pancreatic cancers 2.pre-operative anti-cancer treatment 3. recurrence patients 4.patients with contraindication(hepatic/ respiratory/ renal dysfunction, etc ) 5.pre operative exam: Total bilirubine > 250micromol/L 6. AJCC stage IV 7.operation non radical

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026