None listed
Conditions
Brief summary
The purpose of this study is to compare outcomes of patients undergoing standard or extended lymphadenectomy in pancreaticoduodenectomy for pancreatic ductal adenocarcinoma
Interventions
Pancreaticoduodenectomy for Pancreatic ductal adenocarcinoma with standard or extended lymphadenectomy undergoing by the surgeons from Ruijin Hospital standard lymphadenectomy includes standard lymphadenectomy and No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b lymph nodes stations extended lymphadenectomy includes No8p 12a 12p 14c 14d 16 lymph nodes stations and those in standard lymphadenectomy( No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b) The details of all lymph nodes stations are described as below: No. 5, Suprapyloric lymph nodes; No. 6, infrapyloric lymph nodes; No. 8a, lymph nodes in the anterosuperior group along the common hepatic artery; No. 8p, lymph nodes in the posterior group along the common hepatic artery; No. 12a, lymph nodes along the hepatic artery; No. 12p, lymph nodes along the portal vein; No. 12b, lymph nodes along the bile duct; No. 12c (located next to 12b), lymph nodes around the cystic duct; No. 13a, lymph nodes on the posterior aspect of the superior portion of the head of the pancreas; No. 13b, lymph nodes on the posterior aspect of the inferior portion of the head of the pancreas; No. 14, lymph nodes along the superior mesenteric artery (a & b. right lateral side, c & d. left lateral side ); No. 16, lymph nodes around the abdominal aorta;.No. 17a, lymph nodes on the anterior surface of the superior portion of the head of the pancreas; No. 17b, lymph nodes on the anterior surface of the inferior portion of the head of the pancreas
Sponsors
Study design
Eligibility
Inclusion criteria
1. Pathologic diagnosis of pancreatic ductal adenocarcinoma 2. Signed the informed consents
Exclusion criteria
1. Pathologic diagnosis of other pancreatic cancers 2.pre-operative anti-cancer treatment 3. recurrence patients 4.patients with contraindication(hepatic/ respiratory/ renal dysfunction, etc ) 5.pre operative exam: Total bilirubine > 250micromol/L 6. AJCC stage IV 7.operation non radical