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The role of supplemental oxygen in improving rescuer performance of cardiac chest compressions: A randomised crossover trial

The role of supplemental oxygen in improving rescuer performance of cardiac chest compressions: A randomised crossover trial

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616000773437
Acronym
The SOCC Study
Enrollment
32
Registered
2016-06-14
Start date
2016-07-01
Completion date
2016-08-15
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Performing chest compressions for patients in cardiac arrest is tiring, and as rescuers become more tired their performance has been shown to deteriorate. Quality of Cardiopulmonary Resuscitation (CPR), especially chest compressions, is adversely affected by fatigue and is one of the few factors shown to be independently associated with the likelihood of a person surviving a cardiac arrest. The administration of supplemental low flow oxygen to a rescuer via nasal cannula may slow their fatigue, and increase the length of time that that the rescuer is able to provide good quality chest compressions. We intend to undertake a study to assess the effectiveness of supplemental low flow oxygen on healthy, volunteer rescuers in improving their quality and length of performance of chest compressions on a resuscitation manikin.

Interventions

Participants will each perform three periods of 10 minutes of External Cardiac Compressions (ECC), swapping with their partner (research assistant) every 2 minutes as recommended by the Australian Resuscitation Council. Each participant will perform on a resuscitation practice manikin: 1. ECC with room air (control: ECC-RA) 2. ECC with air via Nasal Cannula (NC) at 4 litres per minute (inspired oxygen fraction 21%)(intervention 1: ECC-A) 3. ECC with oxygen via NC at 4 litres per minute (estim

Participants will each perform three periods of 10 minutes of External Cardiac Compressions (ECC), swapping with their partner (research assistant) every 2 minutes as recommended by the Australian Resuscitation Council. Each participant will perform on a resuscitation practice manikin: 1. ECC with room air (control: ECC-RA) 2. ECC with air via Nasal Cannula (NC) at 4 litres per minute (inspired oxygen fraction 21%)(intervention 1: ECC-A) 3. ECC with oxygen via NC at 4 litres per minute (estimated inspired oxygen fraction 36%)(intervention 2: ECC-O) The NC will be administered administered continuously for the full 10 minutes of CPR. A washout period of 20 minutes will be performed between each arm.

Sponsors

The Alfred
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
19 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

1. Adults 2. Hold qualifications as emergency medicine registrars/consultant, emergency registered nurse or a paramedic 3. Maintain a reasonable level of fitness

Exclusion criteria

1. Any contraindication to nasal cannula (e.g. nasal blockage). 2. Known chronic obstructive pulmonary disease

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026