A comparison of the effects of general and spinal anaesthesia during cesearean section on breastfeeding

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12616000677404

Enrollment

248

Registered

2016-05-25

Start date

2015-06-04

Completion date

2015-09-30

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Purpose: We aim to compare the effects of general anaesthesia and spinal anaesthesia on breastfeeding in caesarean section cases. Method: Pregnant subjects at term who were admitted for caesarean section and whom we could contact via phone were included. Pre-term subjects, those with foetal distress, mentally retarded subjects, those who did not cooperate and those who do not speak Turkish were excluded from the study. The subjects whose infants were admitted to the neonatal intensive care unit after delivery were also excluded. The subjects’ demographic data were recorded. The subjects were divided into two groups: those undergoing general anaesthesia (Group G) and those undergoing spinal anaesthesia (Group S). Breastfeeding was assessed by another anaesthetist at post-operative 1 and 24 hours and 6 months. Findings: A total of 248 subjects were assessed statistically. No statistically significant difference was found between the two groups in terms of first breastfeeding interval. The rate of breastfeeding within 1 hour of delivery was 15.5% in Group G and 21.8% in Group S. The difference was not statistically significant. No statistically significant difference was found between the groups in terms of the rate of breastfeeding within the first 24 hours, either. The rate of breastfeeding in the 6-month period was statistically significantly higher in Group S than Group G. Result: We believe that our study contributes to the literature on investigating spinal anaesthesia and general anaesthesia in breastfeeding subjects. We think that in term pregnancies, the type of anaesthesia does not affect the first breastfeeding interval; however, spinal anaesthesia is superior to general anaesthesia in long-term breastfeeding.

Interventions

The patients’ demographic data were recorded. The patients were divided into two groups based on the type of anaesthesia they received during their caesarean section. Patients were enrolled into the study post-delivery. Non randomized. Group G (General anaesthesia): Preoxygenation was achieved with 100% oxygen for 3 minutes. For induction of general anaesthesia, intravenous 2 mg/kg propofol (Propofol (R), Fresenius-kabi; Istanbul, Turkey), intravenous 1.5 mg/kg, lidocaine (Jetmonal(R) 2%, Adeka; Istanbul, Turkey) and intravenous 0.9 mg/kg rocuronium (Esmeron(R), MSD; Istanbul, Turkey) were administered. After the infant was delivered, intravenous 1 mcg/kg fentanyl (Talinat(R), Vem; Istanbul, Turkey) was administered. For maintenance, 50% O2+ 50% air + 1 MAC sevoflurane (Sevorane(R), Abbvie; Istanbul, Turkey) was administered. Tenoxicam (Tilcotil(R), Deva; Istanbul, Turkey) 20 mg was administered intravenously for postoperative pain. Group S (Spinal anaesthesia): Spinal anaesthesia was performed by inserting a 25G Quince needle at the L3-4 or L4-5 space. Intratekal 12 mg hyperbaric bupivacaine (Bustesin %0.5 spinal heavy (R), Vem; Istanbul, Turkey) was administered. The patients were assessed by another anaesthetist at postoperative 1 and 24 hours and 6 months.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Pregnant subjects at term who were admitted for caesarean section and whom we could contact via phone were included

Exclusion criteria

Pre-term subjects, those with foetal distress, mentally retarded subjects, those who did not cooperate and those who do not speak Turkish were excluded from the study. The subjects whose infants were admitted to the neonatal intensive care unit after delivery were also excluded.

Outcome results