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Effectiveness and safety of pulsed radiofrequency treatment for patients with chronic scrotal pain

In patients complaining of chronic scrotal pain, does pulsed radiofrequency treatment, compared with placebo treatment reduce pain effectively and safely?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616000649415
Enrollment
60
Registered
2016-05-18
Start date
2016-05-20
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Chronic post-surgical scrotal pain is frustrating problem for both, patients and clinicians. We offer placebo controlled clinical trial evaluating the efficacy and safety of extended duration pulsed radiofrequency on ilioinguinal and genital branch of genitofemoral nerves in reduction of pain intensity and analgesic needs

Interventions

Interventional group: (RF) group: in which pulsed radiofrequency (PRF) is applied on the genital branch of genito-femoral nerve and ilioinguinal nerve using Neurotherm 2000 RF generator. After sterilization of the inguinoscrotal region, we targeted the genital branch of genito-femoral nerve through holding the spermatic cord between the thumb and other fingers, then, 2 ml of lidocaine 1% is infiltrated in the skin at the neck of the scrotum. a 22-gauge 10 cm radiofrequency needle with 10 mm acti

Interventional group: (RF) group: in which pulsed radiofrequency (PRF) is applied on the genital branch of genito-femoral nerve and ilioinguinal nerve using Neurotherm 2000 RF generator. After sterilization of the inguinoscrotal region, we targeted the genital branch of genito-femoral nerve through holding the spermatic cord between the thumb and other fingers, then, 2 ml of lidocaine 1% is infiltrated in the skin at the neck of the scrotum. a 22-gauge 10 cm radiofrequency needle with 10 mm active tip is introduced towards the center of the spermatic cord and repositioned to obtain scrotal pain at 50 HZ and less than 1 volt sensory stimulation. Pulsed radiofrequency is applied for 10 minutes (5 cycles, 2 min each) and finally 5 ml of lidocaine 1 % and 1 ml of 40 mg methyl prednisolone is injected. For the ilioinguinal nerve , under ultrasonographic guidance the ilioinguinal nerve were identified just medial to anterior superior iliac spine, a 22-gauge 10 cm radiofrequency needle with 10 mm active tip is introduced towards the nerve and localization is further confirmed by producing scrotal pain at 50 HZ and less than 1 volt sensory stimulation. Pulsed radiofrequency is applied for 10 minutes (5 cycles, 2 min each) and finally 5 ml of lidocaine 1 % and 1ml of 40 mg methyl prednisolone is injected. The procedure was done by senior staff pain clinician.

Sponsors

Diab Fuad Hetta
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

1- patients with chronic scrotal pain (orchialgia) lasting more than 3 month after groin surgeries and failed conservative treatment with non-steroidal anti-inflammatory drugs 2- patients that showed satisfactory response to diagnostic spermatic cord block

Exclusion criteria

1- Patients with other causes of postoperative scrotal pain e.g. epidydmitis, orchitis, and hydrocele 2- Patients on chronic pain killers 3-Patients complaining of groin infection, coagulopathy, psychiatric disorders

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026