None listed
Conditions
Brief summary
The purpose of this study is to determine the effectiveness of incorporating short sprints into current clinical practice guidelines for improving blood glucose management during exercise in individuals with Type 1 Diabetes. We hypothesize that incorporating shorts sprints into any sustained period of physical activity will reduce the incidence of exercise-mediated hypoglycaemia in individuals with Type 1 Diabetes in a free-living setting.
Interventions
This study will follow a randomised crossover design. On three occasions, the participants will wear a continuous glucose monitoring system (CGMS), and an exercise watch for 14 days under free-living conditions. On one occasion, the participants will follow their normal diabetes management during periods of physical activity. In the alternate conditions, the participants will incorporate shorts sprints with their normal diabetes management to any period of sustained physical activity.The partic
This study will follow a randomised crossover design. On three occasions, the participants will wear a continuous glucose monitoring system (CGMS), and an exercise watch for 14 days under free-living conditions. On one occasion, the participants will follow their normal diabetes management during periods of physical activity. In the alternate conditions, the participants will incorporate shorts sprints with their normal diabetes management to any period of sustained physical activity.The participants will be instructed that sprints should be performed with maximum effort. However as this is a "real-life" study we will not be measuring the intensity of the sprint. We will investigate two different sprinting protocols to be performed during sustained (greater than 30 minutes) moderate intensity exercise. Participants will be asked to partake in moderate intensity exercise (running or cycling) at least 3 times a week for at least 30 minutes. This will take place in a real-life, free living setting. Intervention 1: Moderate intensity exercise with a 10 seconds sprint at the start, every 20 minutes during, and at the end of the exercise. Intervention 2: Moderate intensity exercise with a 4 second sprint every 2 minutes, followed by a 10 second sprint at the end of the exercise. We will monitor adherence to sprinting protocols using a GPS exercise watch (worn during exercise) and an exercise diary. All participants will complete intervention 1, intervention 2 and control arms of the study, There will be a 1-2 week washout period between each arm,
Sponsors
Princess Margaret Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
14 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
Type 1 Diabetes duration >1y. - Male and female participants aged between 14 and 35 years old; - Mean (over last 12 months) glycated haemoglobin levels <9%; - Participate in sustained aerobic exercise at least 3 times per week; - Free from any clinical evidence of macrovascular, microvascular or neurological complications associated with Type 1 Diabetes. - Hypoglycaemia aware, as assessed by the Modified Clarke’s Hypoglycaemia Awareness Questionnaire.
Exclusion criteria
- Musculoskeletal injuries; - Other medical conditions where exercise is contraindicated.
Outcome results
None listed