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Pre-surgery aerobic and resistance exercise for rectal cancer patients.

Feasibility and Efficacy of Presurgical Exercise in Survivors of Rectal Cancer Scheduled to Receive Curative Resection

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616000582459
Enrollment
12
Registered
2016-05-05
Start date
2011-02-01
Completion date
2013-11-13
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary objective was to determine the benefits of a pre-surgical exercise programme for rectal cancer patients scheduled for rectal resection. It was hypothesised that: i) between baseline and pre-surgery patients would demonstrate – higher physical functional performance, maintain higher levels of muscle strength and endurance, ii) during the weeks following surgery patients would demonstrate – reduced physical functional performance, reduced muscular strength and endurance iii) between baseline and post-surgery, patients would demonstrate – improved recovery with a higher physical functional performance, maintain higher muscular strength and endurance.

Interventions

This study was a 16-week exercise intervention programme done prior to surgery with assessments undertaken at three time-points: (1) baseline, (2) immediately pre-surgery and (3) 8-week post-surgery follow-up. This is a 16 weeks exercise programme that commenced prior to the schedule surgery. Patients undertook an exercise programme that consisted of two supervised clinic sessions per week. Each supervised exercise session took approximately 60 minutes to complete. Sessions commenced with a 5-mi

This study was a 16-week exercise intervention programme done prior to surgery with assessments undertaken at three time-points: (1) baseline, (2) immediately pre-surgery and (3) 8-week post-surgery follow-up. This is a 16 weeks exercise programme that commenced prior to the schedule surgery. Patients undertook an exercise programme that consisted of two supervised clinic sessions per week. Each supervised exercise session took approximately 60 minutes to complete. Sessions commenced with a 5-minute warm-up consisting of moderate level of aerobic exercise (~60% heart rate maximum (HRmax)), as well as stretching exercises of the major muscle groups: chest, shoulder, biceps, triceps, quadriceps, hamstrings and calf muscles. This was followed by a resistance-training regime that included a series of six exercises targeting the major muscles of the upper- and lower-body. Upper-limb exercises included chest press, seated row and lat pull-down. Lower-limb exercises were leg extension, leg curl and leg press. All exercises were performed through the full range of motion adhering to correct techniques. To ensure the progressive nature of the training programme, patients were encouraged to work past the repetition maximum (RM) prescribed, with resistance increased by 5 – 10% for the subsequent set/training sessions if they were able to exceed the number specified. Progression of resistance followed guidelines previously outlined by Galvao and Newton (2005). The training phases were as follows: week 1 – 2 (two sets 12 RM), week 3 – 5 (three sets of 10 RM), week 6 – 8 (three sets of 8 RM), and week 9 – 10 (four sets of 6 RM). After week 10, the training phases set in week 1 – 2 were resumed to implement a periodised exercise model. A further 20 minutes of aerobic exercise was undertaken. This included such specific activity as walking or jogging on a treadmill; cycling or rowing on a stationary ergometer; or exercising on a cross training machine depending on each patient’s preference. The target intensity was 60 – 80% of the estimated HRmax (220 – age in years) measured using heart rate monitors. The design criteria for the exercise intervention programme were to optimise the stimulus to the cardiovascular and neuromuscular systems while maximising compliance and retention. All sessions were conducted with one-on-one supervision by a qualified and accredited exercise physiologist who ensured safety and adherence to correct lifting techniques. Each session concluded with a 5-minute cool-down with stretching activities similar to the warm-up. Patients were provided with a session log in which to record their attendance, exercise weights, repetitions and sets.

Sponsors

Edith Cowan University
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Primary purpose
Prevention

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

The eligibility inclusion criteria included patient scheduled for surgery for localised rectal cancer; and medical clearance to participate in an exercise programme from their general practitioner.

Exclusion criteria

The exclusion criteria is patient must not have any acute illness or any musculoskeletal, cardiovascular or neurological disorder that could inhibit the ability to walk 400m unassisted and partake in upper- and lower-body exercises.

Outcome results

None listed

Source: ANZCTR · Data processed: Jul 23, 2026