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A study looking at the reproducibility of Magnetic Resonance Imaging (MRI) Simulation Scans for Radiotherapy Planning

Uncertainty in Magnetic Resonance Imaging (MRI) Simulation Scans for Radiotherapy Planning

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12616000523404
Acronym
HOHO
Enrollment
60
Registered
2016-04-22
Start date
2016-03-03
Completion date
2017-04-05
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will evaluate the reproducibility of magnetic resonance imaging (MRI) setup of patients in the radiotherapy treatment position and assess how this impacts the image quality for radiotherapy planning and treatment delivery. Who is it for? You may be eligible to join this study if you are aged 18 years or above and have been diagnosed with prostate, head and neck, central nervous system, rectal, cervix or lung cancer. Study details: Patients would otherwise be undergoing an MRI scan in the radiotherapy department for their cancer treatment or other research purposes. Patients will undergo a planning MRI scan in the treatment position then the patient would then get off the MRI couch and be set-up for a second MRI scan with limited MRI sequences. The main purpose of this study is to determine the consistency of positioning and the impact of MRI distortion, landmark positions and contours between scans.

Interventions

The intervention involves an additional MRI scan for participants that will only be used for the purpose of the study and not for the radiotherapy treatment planning. Participants would otherwise be attending for an MRI scan for the purposes of planning for their radiotherapy treatment (simulation) but the intervention is an additional scan. The scan will be performed by a suitably qualified allied health professional. The scan will be performed at only one time point and on the same day as thei

The intervention involves an additional MRI scan for participants that will only be used for the purpose of the study and not for the radiotherapy treatment planning. Participants would otherwise be attending for an MRI scan for the purposes of planning for their radiotherapy treatment (simulation) but the intervention is an additional scan. The scan will be performed by a suitably qualified allied health professional. The scan will be performed at only one time point and on the same day as their radiotherapy planning MRI or clinical research MRI and the additional scan will take approximately 15 minutes. The additional MRI scan will be completed with fewer sequences than the first scan. The sequences used will be one anatomical and one functional imaging sequence (DWI).

Sponsors

Liverpool Hospital
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

- Aged 18 years or older - Patients undergoing a planning MRI for their radiotherapy treatment or research purposes for prostate, head and neck, central nervous system, rectal, lung or cervix cancer

Exclusion criteria

- Patient refusal - Contraindication to MRI, such as pacemakers and embodied metal objects, as assessed with the MRI Safety Questionnaire - Patients with severe claustrophobia or who are unable to lie still - Inability to give informed consent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026