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High intensity progressive resistance training for postmenopausal women with low to very low bone mass: The LIFTMOR trial

A randomized controlled trial to determine the effectiveness of high intensity progressive resistance training for postmenopausal women with low to very low bone mass

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12616000475448
Acronym
LIFTMOR - Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation
Enrollment
101
Registered
2016-04-12
Start date
2014-05-20
Completion date
2015-11-05
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Bone responds to mechanical stimuli, with the greatest response from high loads being applied quickly. High loads have remain unexamined in postemenopausal women with low bone mass due to the perceived risk of injury. The LIFTMOR trial was developed to see if the loads required to obtain the a greater bone response are both safe and effective in postmenopausal women with low to very low bone mass.

Interventions

The intervention arm consists of a high intensity progressive resistance training program. Participants attend two 30-minute exercise sessions per week. Each sessions is conducted in groups of up to 6 participants and supervised by either a physiotherapist or exercise physiologist. The high intensity exercise program consists of four compound exercises (deadlift, overhead press, jumping chin ups and back squat) for 5 sets of 5 repetitions (>85% 1 repetition maximum). Compliance and weight lifted

The intervention arm consists of a high intensity progressive resistance training program. Participants attend two 30-minute exercise sessions per week. Each sessions is conducted in groups of up to 6 participants and supervised by either a physiotherapist or exercise physiologist. The high intensity exercise program consists of four compound exercises (deadlift, overhead press, jumping chin ups and back squat) for 5 sets of 5 repetitions (>85% 1 repetition maximum). Compliance and weight lifted is monitored via training manuals which each participants completes at the end of each session.

Sponsors

Griffith University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Postmenopausal women with low bone mass (T-score < -1.0)

Exclusion criteria

Musculoskeletal or medical conditions affecting the ability to perform exercise, medications or medical conditions known to effect bone health, cancer, recent radiation exposure or fracture and current engagement in resistance training

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026