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Troponin levels in patients undergoing spinal surgery:prone versus supine position.

Prospective controlled cohort study of Troponin I levels in patients undergoing spinal surgery: Prone versus supine position

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12616000421437
Acronym
TropoSS
Enrollment
91
Registered
2016-04-01
Start date
2013-04-05
Completion date
2015-11-20
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a novel study to determine if patients lying in the prone position for spinal surgery develop evidence of mild cardiac bruising as evidenced by a serial serum Troponin rise and ECG abnormalities We suspect that, after prolonged positioning in the prone position, some patients develop evidence of mild cardiac bruising. If so, we intend to study factors that may be predictive of such cases. If confirmed, our study would indicate that all patients undergoing prone position spinal surgery should be consented for the possibility of developing cardiac bruising. If certain risk factors could be identified and if supine position surgery was also simultaneously indicated, then the risk of cardiac bruising would have to be evaluated in conjunction with other pros and cons of each approach, so that the individual could decide upon the best approach for their spinal surgery: i.e. anterior or posterior approach.

Interventions

Exposure is undergoing spinal surgery in the prone position for the duration of the operation, with blood samples taken up to 24 hours following surgery. Review of state-wide medical records at 30 days post surgery.

Sponsors

The Townsville Hospital Neurosurgical Department
Lead SponsorHospital

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

All adult patients undergoing elective spinal surgery for degenerative conditions

Exclusion criteria

Paediatric population, oncologic surgery, emergency surgery

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026