None listed
Conditions
Brief summary
Research Plan This research will examine the benefits of HIIT on IR metabolic syndrome and polycystic ovarian syndrome women. A controlled trial was conducted in Armidale for 12 weeks. Metabolic syndrome women with or without PCOS aged between 18 to 70 years were recruited to the high intensity interval training group (HIIT G) or the control group (CG). The primary purpose of this study is to examine the benefits of HIIT on insulin resistance in men and women with metabolic syndrome. Research Hypothesis HIIT induces metabolic changes and improves IR, glucose homeostasis and lipid metabolism HIIT induced regulation of insulin will reduce androgen production HIIT enhances skeletal muscle oxidative capacity Aims To accomplish the primary purpose of this study the following assessments will be conducted:- 1. Evaluate the percentage of change in body composition parameters. 2. Assess the level of change in hormonal parameters. 3. Assess the level of change in blood glycaemic parameters 4. Evaluate the level of change in blood lipid profile 5. Evaluate the percentage of improvement in parameters of cardiovascular fitness, heart rate variability and telomere length. Research Plan This research will examine the benefits of HIIT on IR metabolic syndrome and polycystic ovarian syndrome women. A controlled trial was conducted in Armidale for 12 weeks. Metabolic syndrome women with or without PCOS aged between 18 to 70 years were recruited to the high intensity interval training group (HIIT G) or the control group (CG). Two information and screening sessions will be conducted for participants before the intervention. Information regarding HIIT, exercise testing procedures, blood tests and the intervention study will be discussed. Participants will be asked to complete a health questionnaire. Based on the information provided by the participant and the health questionnaire, decision will be made on eligibility for participation. During the screening session consent forms will be signed. HIIT G participants will undergo supervised high intensity exercise training on bicycle ergometers 3 times/week. A HIIT session will be a 5 min warm up, 3 sets of HIIT for 20 seconds (3×20), 2 minutes of low intensity exercise after each HIIT set, 5 min cool down period and stretching. Participants assigned to the control group will continue with their usual care and will not participate in supervised exercise sessions. Both intervention groups will be provided with an activity journal to record their daily physical activity. Pre training assessment for peak VO2 will be done using an incremental exercise test on an exercise bike. Heart rate will be monitored during each exercise session. Measurements for body composition, blood essays for glycaemic markers, hormones and lipids will be conducted at baseline, 6 weeks, 12 weeks and 6 week post intervention completion.
Interventions
This study will examine the effects of high intensity interval training (HIIT) on IR in women with metabolic syndrome and PCOS
This research will be a controlled trial in Armidale for 12 weeks. Metabolic syndrome women with or without PCOS aged between 18 to 70 years will be recruited based on the day of enrollment to the high intensity interval training group (HIIT G) or the control group (CG). HIIT G participants will undergo supervised HIIT on bicycle ergometers 3 times/week.
A HIIT session w
This study will examine the effects of high intensity interval training (HIIT) on IR in women with metabolic syndrome and PCOS This research will be a controlled trial in Armidale for 12 weeks. Metabolic syndrome women with or without PCOS aged between 18 to 70 years will be recruited based on the day of enrollment to the high intensity interval training group (HIIT G) or the control group (CG). HIIT G participants will undergo supervised HIIT on bicycle ergometers 3 times/week. A HIIT session will be: 5 min warm up (low intensity exercise performed at 50% VO2 max) 3 sets of HIIT for 20 seconds (3×20) performed at 95% VO2 max, 2 min low intensity exercise at 30% VO2 after each HIIT set 5 min cool down at 30% VO2 max Stretching of hamstrings, quadriceps, hip adductors, hip abductors and calf muscles for a total time period of 3 minutes. CG will continue with their usual care and will not participate in HIIT sessions. The mode of administration will be one-on-one consultation. The intervention will be administered by an exercise physiologist.
Sponsors
University of New England
Study design
Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used) (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Women aged between 18 to 70 years and any 3 out of the following 5 possible inclusion criteria waist circumference > 80cm, insulin resistance with or without glucose intolerance, high triglycerides, low high density lipoprotein and raised blood pressure.(> 135mmhg systolic and > 85mmhg diastolic). Women with PCOS. If women have PCOS with metabolic syndrome they should not be undergoing fertility treatment.
Exclusion criteria
Those under 18 years of age, Older or younger people may respond differently. Those who are deemed not to have the capacity to voluntarily participate in this exercise study. Those who are unable to participate under their doctor's recommendation. Those with arthritis of knees and hip may aggravate their condition with high intensity exercise. Patients with known cardiovascular disease (e.g. angina) and the following co-morbid conditions (mobility impairment, sleep apnoea, fatty liver- or renal-disease). Smokers will be excluded.
Outcome results
None listed