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Can electrogastrography (EGG) detect abnormal activity of the stomach in babies with feeding difficulties

Continuous wavelet analysis of postprandial EGGs suggests sustained gastric slow waves may be slow to develop in infants with colic

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12616000313437
Acronym
CBS (Colicky baby study)
Enrollment
49
Registered
2016-03-10
Start date
2013-02-25
Completion date
2014-12-04
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aetiology of infant colic is poorly understood with little evidence regarding the development of gastric and intestinal motility. Its occurrence is a common concern to nursing mothers particularly in view of the fact that there are currently no tests that can readily distinguish any underlying pathology. The aim of the current work was to determine the incidence of gastric rhythm disorders in infants by comparing electrogastrography (EGG) signals by continuous wavelet analysis, to compare EGG patterns of non colicky versus colicky infants. Post prandial EGG recordings were obtained from 1) 26 breast fed non-colicky infants and 2) 23 breast fed colicky infants.

Interventions

Exclusively breast-fed, non-colicky babies and exclusively breast-fed babies diagnosed with infant colic were recruited by advertisement. The mothers of those with infant colic completed a questionnaire regarding symptomatology. A respiratory belt (ADInstruments MLT1132; Sydney, Australia) was placed around the mid-thorax of the baby. EGG recordings were taken from an array of adherent bipolar silver/silver chloride electrodes (Ambu N-00-S/25; Copenhagen, Denmark) applied to the anterior surface

Exclusively breast-fed, non-colicky babies and exclusively breast-fed babies diagnosed with infant colic were recruited by advertisement. The mothers of those with infant colic completed a questionnaire regarding symptomatology. A respiratory belt (ADInstruments MLT1132; Sydney, Australia) was placed around the mid-thorax of the baby. EGG recordings were taken from an array of adherent bipolar silver/silver chloride electrodes (Ambu N-00-S/25; Copenhagen, Denmark) applied to the anterior surface of the stomach. A total of 6 electrodes (4 recording, 1 common, 1 earth) were applied and connected to an electrically isolated recorder (AD Instruments Octal Bioamp ML138 and 8/SP Powerlab A/D converter; Sydney, Australia). Voltage readings from the respiratory belt and EGG recordings were for 3.5 hours (one recording per baby), based on previous research, including whilst the baby was sleeping after feeding

Sponsors

Massey University
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
1 Months to 4 Months
Healthy volunteers
Yes

Inclusion criteria

Infants recruited had ongoing signs of colic as diagnosed by a clinician and were screened by questionnaire to ensure that the child exhibited one or more of the reported characteristics; paroxysmal crying of a higher pitch with more tenseness and irregularity, paroxysmal crying particularly in the evening, paroxysmal crying for periods of more than 3 hours per day, paroxysmal crying for more than 3 days per week and paroxysmal crying more than three weeks duration, paroxysmal crying commencing during the first week of life and peaking during the second month of life. Infants recruited in the control group had no signs of colic as diagnosed by a clinician and were screened by a questionnaire to ensure that the child did not exhibit any of the above reported charachteristics

Exclusion criteria

Infants who were mechanically unwell

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026