None listed
Conditions
Brief summary
The primary purpose of this exercise study (in collaboration with JCU) is to investigate if regular physical activity in a group or individually improves the psychological effects whilst on hormone and radiation treatment. We aim to recruit 117 patients. The exercise program will be conducted by the exercise physiologists at the JCU clinic. Who is it for? You may be eligible to participate in this study if you have been recently diagnosed with localised prostate cancer, for which you have been scheduled to begin a combination of radiotherapy and Eligard hormone treatment. You must not have commenced Eligard hormone treatment more than one month previously. Study details: Participants enrolled in this study will be randomly allocated (by chance) to one of three groups. *The first group involves completing a group exercise program. *Participants allocated to the second group will complete an individual exercise program. *Participants allocated to the third group will not complete any exercise program, but will simply continue with their cancer treatment as normal. Participants allocated to either of the first two groups, i.e. the exercise program groups, will complete a 60 minute training session either as part of a group or on their own, three times per week for the duration of their hormone and radiotherapy treatment, or for a maximum of eight months. Exercise sessions involve aerobic/light impact activity and resistance/light impact activity. The program will alternate each week. Week 1: *2 sessions of aerobic/light impact activity *1 session of resistance/light impact activity Week 2: *1 session of aerobic/light impact activity *2 sessions of resistance/light impact activity Researchers will assess the efficacy of the exercise programs using questionnaires, s fitness test before starting the program and after finishing the program, and through a brief 15 minute interview with participants at the end of their radiation treatment. It is hoped that the findings from this trial will provide further information on the benefits of exercise during treatment for prostate cancer, and on which format of exercise is preferable and most beneficial for patients.
Interventions
Two arms in intervention group:
Arm 1: Group exercise
Arm 2: Individual exercise
Both arms will be subjected to identical exercise interventions which
is Moderate to vigorous physical Activity (MVPA); 60 minutes of MVPA, 3 days per week until completion of radiation treatment but no more than eight (8) months.
They will start the exercise program within a month of hormone injection.
Aerobic training target will be 60-85% maximum heart rate and will be calculated for each participant from esti
Two arms in intervention group: Arm 1: Group exercise Arm 2: Individual exercise Both arms will be subjected to identical exercise interventions which is Moderate to vigorous physical Activity (MVPA); 60 minutes of MVPA, 3 days per week until completion of radiation treatment but no more than eight (8) months. They will start the exercise program within a month of hormone injection. Aerobic training target will be 60-85% maximum heart rate and will be calculated for each participant from estimated maximum heart rate minus age. Resistance training intensity will be manipulated from 6-12 RM, using 1-4 sets per exercise to support strength gains. Exercise sessions involve aerobic/light impact activity and resistance/light impact activity. The program will alternate each week. Week 1: *2 sessions of aerobic/light impact activity *1 session of resistance/light impact activity Week 2: *1 session of aerobic/light impact activity *2 sessions of resistance/light impact activity The exercise sessions will be performed and supervised by an accredited Exercise physiologist for both arms. In arm 1 (group) will have 2-10 participants. The exercise physiologist will monitor adherence by registering attendance for each session.
Sponsors
Townsville Hospital and Health Service
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Newly diagnosed localised prostate cancer * All participants to be able to walk 400 meters completed at pre-assessment by exercise physiologist * Provide written consent * Able to start exercise program within one month of Eligard hormone treatment * Obtain medical clearance prior to participating in the intervention All participants must be scheduled to undergo radiotherapy in combination with Eligard hormone treatment
Exclusion criteria
* Advanced or metastatic prostate cancer * Unable to walk 400m unassisted * Have musculoskeletal, cardiovascular and/or neurological disorders that could inhibit them from exercising (determined by patient’s physician) * Cognitive impaired
Outcome results
None listed