None listed
Conditions
Brief summary
This pilot randomised controlled trial will be the first to investigate if supervised progressive resistance training (strength training) is safe and feasible for adolescents and young adults with Prader Willi syndrome aged 13-39 years. It will also investigate the effect of the training on body composition (including muscle mass), muscle strength, muscle performance, and physical activity. Twenty-two adolescents and young adults with Prader Willi syndrome will be recruited through the Prader Willi Syndrome Association of Victoria and through the Prader Willi Syndrome register. Participants will be randomly allocated to either a 10-week twice a week community gymnasium based progressive resistance training program supervised by a physiotherapist (n=11) or a waitlisted control group (n=11). The training program will comprise 7 exercises on pin-loaded weight machines: 3exercises for the arms, 3 exercises for the legs and 1 exercise for the trunk which will take 45-60 minutes to complete each session. Participants will be assessed before they start the intervention and again after they complete the intervention.
Interventions
Participants in the experimental group will complete a 10-week progressive resistance training program. They will be taught 7 exercises: three exercises for the upper limbs, three exercises for the lower limbs and one exercise for the trunk. All exercises will be completed on weight machines in a local gymnasium and each exercise session will take approximately 60 minutes. The training program is based on the recommendations of the American College of Sports medicine and will comprise 3 sets of
Participants in the experimental group will complete a 10-week progressive resistance training program. They will be taught 7 exercises: three exercises for the upper limbs, three exercises for the lower limbs and one exercise for the trunk. All exercises will be completed on weight machines in a local gymnasium and each exercise session will take approximately 60 minutes. The training program is based on the recommendations of the American College of Sports medicine and will comprise 3 sets of 12 repetitions of each exercise at a training intensity of 12RM. The weight lifted in each exercise will be increased when 3 sets of 12 repetitions of an exercise can be completed. Two-minute rest periods will be given between each exercise set. The program will be conducted twice weekly for 10 consecutive weeks. Participants will complete the program one-on-one with a physiotherapist. Adherence will be monitored using an exercise log-book.
Sponsors
La Trobe University
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
13 Years to 39 Years
Healthy volunteers
No
Inclusion criteria
(1) Ability to follow simple instructions in English, (2) fit and well enough to participate in a strength training program and (3) a diagnosis of Prader Willi syndrome
Exclusion criteria
Participation in a strength training program in the 3 months prior to the start of the study.
Outcome results
None listed