None listed
Conditions
Brief summary
Aims: The aim of this project is to assess the effects of water-based exercise training in people with stable heart disease. This study is being conducted in conjunction with an acute study assessing the physiological effects of a single submerged session compared to a single session of matched intensity land-based exercise. Justification: Exercise is an important component of rehabilitation and preventing recurrent heart problems in people with heart disease. However, exercise participation is sub-optimal in this population and increasing the range of exercise options for people with heart disease may increase exercise participation. For example, water-based exercise may be more appealing to people with heart disease who have other health issues, such as arthritis or obesity, which may make land-based exercise difficult or painful. Furthermore, preliminary research suggests that water-based exercise may have additional vascular and brain benefits due to the effects of water immersion on blood flow. However, this has not previously been investigated in people with heart disease. Participants: Patients who have had a heart attack or bypass surgery at least six months prior to enrolment, or documented blockages in the arteries of their heart based on the results of an angiogram (a scan of the heart) will be recruited to the study. Participants must be medically stable prior to participation and not be undertaking a formal exercise program. Design and methods: 60 participants will be randomised into one of three groups for the duration of a 12 week program: *12 weeks of land-based exercise * 12 weeks of water-based exercise * A control group who will maintain their usual activities for 12 weeks. Strength, fitness, vascular function, brain blood flow, body composition, blood profiles and aspects of cognition will be assessed before and after the 12 week period. Vascular function will be assessed fortnightly during the 12 week period in a subgroup of participants.
Interventions
Study B is part of a broader project investigating the effects of water-based exercise in people with coronary heart disease. This study will involve a 12 week randomised controlled trial involving participants who will be randomised into one of three groups: *12 weeks of land-based exercise * 12 weeks of water-based exercise * A control group who will maintain their usual activities for 12 weeks. The training groups will be supervised by a health professional (majority of sessions supervised by a physiotherapist) and group training sessions (maximum of 10 participants) will be conducted three times per week, for one hour and 10 minute sessions, for 12 weeks (36 sessions total). The training programs will commence and conclude with 5 minutes of light aerobic activity (e.g. walking) and stretching. Moderate intensity exercises will alternate resistance (strength) and aerobic (fitness) stations. There will be 7 resistance and 8 aerobic stations lasting for 90 seconds, with 30 seconds of active recovery between exercises. Participants will build up to completing 2 circuits per session. During water-based exercise participants will be submerged to their xiphoid process (lower chest) in a heated swimming pool. Aerobic exercises will be monitored and matched by heart rate (60-80% of a participant’s heart rate maximum) and rating of perceived exertion (11-14 rating on the Borg Rating of Perceived Exertion Scale). Training will commence at approximately 60% of participants’ VO2peak and progress to 80% over the course of the training, as individually tolerated. Water-based aerobic exercises will include jogging, quick stepping/ jumping and high knees. Land-based aerobic exercises will include cycling, treadmill jogging and recumbent cycling. Resistance exercises will be matched for muscle group, Borg rating (between 11-14) and quantified resistance per station. Water-based exercises will utilise custom-designed resistance equipment (paddles), developed by this research team previously. Water-based resistance exercises will include; shoulder flexion and extension, shoulder abduction and adduction, hip flexion and extension, knee flexion and extension and hip abduction. Land-based exercises will include; shoulder flexion/ extension, modified shoulder abduction/ adduction, knee extension, hamstring curls, hip flexion/ extension and hip abduction. Resistance will be provided by machines, pulleys, free weights and ankle weights and the weight lifted can be used to quantify resistance. Participant attendance will be recorded for each session, as will a selection of perceived exertion, heart rate and resistance measures for each session. Strength, fitness, vascular function, brain blood flow, body composition, blood profiles and elements of cognition will be assessed before and after the 12 week period. Vascular function will be assessed fortnightly during the 12 week period in a subgroup of 14 participants from each of the training groups. Participants will be invited to take part in this as they enroll chronologically, until we reach the 14 participants required.
Sponsors
Study design
Eligibility
Inclusion criteria
*Stable, documented coronary heart disease and be at least 6 months following a myocardial infarction, coronary artery bypass graft or percutaneous coronary intervention * Have been taking stable medical therapy for the last 2 months * Be able to participate in exercise training 3 days per week and organise their own transport
Exclusion criteria
*Renal impairment, hepatic impairment, proteinurea or hyperuricaemia * Left ventricle ejection fraction below 45% * Musculoskeletal or neurological condition or injury that precludes exercise training * Any current or recent neoplasms or cancer treatment * Current smokers * Premenopausal females (due to the potential effects of hormonal cycle on vascular assessment) *Currently participating in a formal exercise program at least 3 times per week, or have done so in the last 6 weeks