None listed
Conditions
Brief summary
This project aims to investigate if a high intensity interval training (HIIT) program offers greater improvements, than moderate intensity continuous exercise, for intra-abdominal fat, fitness, inflammation, cardiovascular risk factors, and exercise adherence. The project will also investigate whether HIIT can be successfully integrated into a hospital-based cardiac rehabilitation program as a practical and safe alternative to moderate intensity exercise. We expect high intensity interval training will be a safe and practical option. This will lead to the, development of a protocol to guide cardiac rehabilitation programs on how to incorporate HIIT as a standard exercise option for patients.
Interventions
High intensity interval training
Isocaloric exercise protocol to usual care
31 minutes exercise (including 3minute warm-up and 3 minute cool down)
- Following warm-up, 4 x 4minute high intensity intervals (85-95% VO2 peak)
- Interspersed with 3minute intervals (3 in total) of moderate intensity intervals (60-70% VO2 peak)
Various aerobic exercise machines will be used, depending on preference and musculoskeletal limitations. These include treadmill, cycle ergometer, cross-trainer, or rowing erg
High intensity interval training Isocaloric exercise protocol to usual care 31 minutes exercise (including 3minute warm-up and 3 minute cool down) - Following warm-up, 4 x 4minute high intensity intervals (85-95% VO2 peak) - Interspersed with 3minute intervals (3 in total) of moderate intensity intervals (60-70% VO2 peak) Various aerobic exercise machines will be used, depending on preference and musculoskeletal limitations. These include treadmill, cycle ergometer, cross-trainer, or rowing ergometer. Training will be adapted for home-based exercise equipment or walking program. Stage 1: Four weeks hospital program = 2 x supervised sessions and 1 home-based session per week. All supervised classes will be delivered by an Accredited Exercise Physiologist. Stage 2: Eight weeks home-based program (3 sessions/week) with weekly telephone support These weekly 5-10 minute calls will be provided by a qualified health professional (e.g. nurse or exercise physiologist) to discuss adherence and other issues (e.g. symptoms). Stage 3: Maintain home-based program (at least 3 sessions/week) for a further 9 months. Follow-up testing at 6 months and 12 months from baseline measures. Adherence to exercise program will be monitored at supervised rehabilitation sessions (initial 4 weeks), home exercise log with weekly telephone follow-up (for subsequent 8 weeks), FitBit device data (for a sub-group of patients), and 7-day accelerometer data at each testing period (4 weeks, 13 weeks, 6 months, 12 months). Compliance will be assessed as 70% adherence to recommended exercise program (intensity, type, time, and frequency) Dietary control will also be monitored on 2 days at each testing period by a dietitian administered 24-hour recall.
Sponsors
University of Queensland (School of Human Movement and Nutrition Sciences)
Study design
Allocation
Randomised controlled trial
Primary purpose
Prevention
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Coronary artery disease patients who are eligible to attend the Wesley Hospital Phase II cardiac rehabilitation program will be offered the opportunity to participate in the study. Diagnostic criteria for coronary artery disease is confirmation of the disease in at least one vessel by a cardiologist following coronary angiogram. Patients may have a history of myocardial infarction (MI) > 4 weeks, percutaneous coronary intervention (PCI) > 3 weeks, coronary artery bypass graft (CABG) surgery > 4 weeks, valve surgery > 4 weeks, and heart failure. Access to a smartphone or computer will also be required.
Exclusion criteria
Absolute or relative contraindications to exercise testing as per American College of Cardiology and American Heart Association guidelines, including but not limited to: Unstable angina; Unstable arrhythmias, Significant valvular disease; Uncompensated heart failure; Pulmonary disease; Uncontrolled hypertension (systolic blood pressure > 200 mmHg and/or diastolic blood pressure >110 mmHg); Renal failure (Chronic Kidney Disease stages III-V); Orthopaedic/neurological limitations; Physical impairment limiting the ability to exercise. Additionally patients will be excluded for: Planned operations during the research period; Drug or alcohol abuse; Planning to or participation in another study; Not willing to sign the consent from; Females pregnant or expecting to be pregnant during the study period; Any other reason which would limit their ability to participate in this study.
Outcome results
None listed