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Use of the six minute walk test to predict recovery and complications in morbidly obese patients undergoing elective surgery

In severely obese patients presenting for elective surgery, can the six minute walk test predict recovery and medical complications?

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615001264572
Enrollment
285
Registered
2015-11-19
Start date
2017-02-08
Completion date
2017-12-01
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Wollongong Hospital is a large regional hospital that performs approximately 13 000 episodes of operative care per year. The range of surgery performed covers all areas apart from cardio-thoracic, including neurosurgery, vascular, orthopaedics, urology, ENT general, colo-rectal, endoscopy, imaging, obstetrics and gynaecology, general paediatrics, and plastic surgery. The anaesthesia department at Wollongong Hospital has an audit and research focus particularly in the fields of education, obesity, and geriatric care. Australian Bureau of Statistics data report that 62.8% of adult Australians were overweight or obese in 2011-12. Of this number, approximately 12% had a body mass index (BMI) greater than or equal to 35, which, in the presence of comorbidities, has been defined as morbid obesity. Local data show that at least 13% of patients undergoing elective surgery at Wollongong Hospital each year are morbidly obese. Most of the literature suggests that morbidly obese patients have higher rates of clinical complications in the post-operative period than the non-obese although this finding has not been universally reported. Assessment of risk in obese patients cannot accurately be based on the presence of obesity alone. Measurement of functional capacity pre-operatively is considered essential for useful risk stratification and prediction of post-operative outcomes. Cardiopulmonary exercise testing (CPET) is the gold standard for assessing cardio-respiratory fitness. However, CPET is expensive, resource-intensive, and requires a dedicated specialist laboratory and trained technicians. In contrast, the six minute walk test (6MWT) is a simple and cheap test for evaluation of cardio-respiratory function that has compared well to CPEX in previous studies. It may be ideal for assessing functional capacity in morbidly obese patients as it can be performed by existing staff in a pre-operative assessment area and has been shown to be safe for morbidly obese patients in multiple papers. There are currently no published data on the use of the 6MWT as a screening tool to predict high risk in obese patients undergoing surgery. The aim of this study is to assess the ability of the 6MWT to predict postoperative functional recovery and medical complications in morbidly obese patients in Wollongong Hospital who attend a pre-admission assessment clinic (PAC). Identification of this subset of patients would allow peri-operative teams to target further investigations, optimise surgical planning, and stratify the intensity of intra-operative and post-operative care. With these strategies, it may be possible to decrease morbidity and mortality and the associated healthcare costs to the community.

Interventions

Performance of the six minute walk test. This measures the distance that a patient can walk in 6 minutes and is follows steps delineated by a standard operating procedure. This will occur in the pre-operative assessment clinic and be supervised by a research assistant who will be trained in supervision of the test.. Performance of spirometry, measurement of waist and hip circumferences, and of serum NT pro-BNP will also occur in the pre-operative assessment clinic. These are study measures and a

Performance of the six minute walk test. This measures the distance that a patient can walk in 6 minutes and is follows steps delineated by a standard operating procedure. This will occur in the pre-operative assessment clinic and be supervised by a research assistant who will be trained in supervision of the test.. Performance of spirometry, measurement of waist and hip circumferences, and of serum NT pro-BNP will also occur in the pre-operative assessment clinic. These are study measures and are not measured routinely. Patients visit the pre-operative assessment clinics between one day and 6 weeks prior to their scheduled date of surgery.

Sponsors

Natalie Smith
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Consent Age => 18 years BMI => 35 at pre-admission clinic Booked for elective non-cardiac surgery at Wollongong hospital

Exclusion criteria

Inadequate time to complete the 6MWT pre-operatively Presence of medical contra-indications to the 6MWT test as per American Thoracic Society guidelines Pregnancy

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026