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Kiwifruit modulation of post-prandial glycaemia and its cognitive effects

In healthy subjects, does the dietary intervention of kiwifruit, compared to a standard breakfast, effectively control blood glucose responses and enhance cognition.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615001259538
Enrollment
20
Registered
2015-11-18
Start date
2014-09-01
Completion date
2014-09-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The trial involves 20 subjects who each have to consume one breakfast per week over 4 weeks, in random order. The 4 breakfasts are: (1) weetbix, (2) weetbix + guar gum (a widely used food grade ingredient), (3) weetbix + kiwifruit, and (4) weetbix + kiwifruit + guar gum. They then have to have 7 small diabetic-type finger prick tests of blood glucose over a period of three hours and do three short cognitive tests of brain function. The aim of the study is to determine whether or not kiwifruit, and kiwifruit interacting with guar gum leads to an attenuation of the glycaemic response that helps sustain cognitive performance several hours after a meal.

Interventions

Four diets: (1) WeetBix (47.3 g) (2) WeetBix (47.3 g) + Kiwifruit (200 g) (3) WeetBix (47.3 g) + Guar gum (10 g) (4) WeetBix (47.3 g) + Guar gum (10 g) + kiwifruit (200 g) Duration: Participants were given 15 minutes to consume each breakfast. Frequency: Participants consumed each breakfast one morning a week, over a period of four weeks. Each breakfast (1-4) was only consumed once by each participant. The wash out period was one week for each participant, and they were asked to fast for 12

Four diets: (1) WeetBix (47.3 g) (2) WeetBix (47.3 g) + Kiwifruit (200 g) (3) WeetBix (47.3 g) + Guar gum (10 g) (4) WeetBix (47.3 g) + Guar gum (10 g) + kiwifruit (200 g) Duration: Participants were given 15 minutes to consume each breakfast. Frequency: Participants consumed each breakfast one morning a week, over a period of four weeks. Each breakfast (1-4) was only consumed once by each participant. The wash out period was one week for each participant, and they were asked to fast for 12 hours before each trial, to eliminate the effects of other food on glucose levels.

Sponsors

New Zealand Institute for Plant and Food Research
Lead SponsorGovernment body

Study design

Allocation
Non-randomised trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
21 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

Non-diabetic

Exclusion criteria

Fasting blood glucose > 7 mmol/L

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026